Neonatal Sepsis Flashcards
Neonatal sepsis presents how
Anything
GEN-lethargy ,irritable ,temp instability
RS-distress
CVS-bradycardia
GIT-poor feeding,vomiting,and distention ,jaundice
CNS-seizure ,tense fontanell,opisthotonos
Neonatal sepsis catogories
Early onset before 72 h
Late onset after 72h -3 months
Early onset sepsis risk factors4
PROM
Chorioamnionitis
Maternal fever-UTI
Preterm
Organisms come from where in early onset
Fecal o vaginal origin>membranes>amniotic fld>res tract of fetus>sepsis>meningitis
Ix in neonatal sepsis 5
FBC Blood cultures CRP Xray If meningitis suspect CSF
CRP rices when and how does it help
In diagnosis
Rises 12-24 hours later
One value normal can’t exclude sepsis
It 2normal sepsis unlikely
Organisms in early sepsis
Gram pos- group B streptococci
Listeria monocytogen
Gram neg-ecoli and others
Treatment in early sepsis given when what
When to stop
When to check CSF
Broad spectrum AB wo waiting for reports Genta and c pen
If cultures neg CRP normal omit in 48hrs
If culture positive O any CNS signs
Late onset sepsis sources 2
Usually from environment
Also
From birth canal
Organisms in late sepsis 5
Common -Staph epididimis
Staph aureus
Pseudomonas
Candida
Less common-group B strepto
Listeriap
Treatment in late sepsis
Initially to cover what if not responding
Staph and gram negatives -flucloxacc and Genta
Not resp-Vancomycin
If meningitis suspected antibiotics
Penicillin and 3rd gen cephalosporin;cefotaxim)
Complications of meningitis early and late
Early -ventriculitis,abscess,hydrocephalus
Late-SN deafness ,cp
Grp B streptocc sources 2
Vaginal
Feacal
How is GBS transmitted to baby
At delivery
Ascending infection
