Neonatal Derm,Genetic Skin Dz, Dz Pigmentation, Common Skin Dz Flashcards
Erythema toxicum
- eosinophils
transient neontal pustular melanosis
- most common AA
- more leukocytes than eosinophils
Stuger-Weber Sy
-Port wine stain of opthalmic branch of trigeminal nerve (V1) -Ass w/ ipsilateral cerebral vascular malformations
Klippel-Trenaunay Sy
- Port-wine lower extremities -Ass w/ soft tissue &/or limb overgrowth + venous varicosities
Parkes-Weber Sy
- Port-wine lower extremities -Ass w/ marked limb overgrowth both length & girth
Nevous Sebaceuos
-yellow to salmon, hairless plaque has waxy texture -Tx- prepubertal removal since risk of basal cell carcinoma
Nevous spilus
- well-demarcated, tan or light-brown, non-hairy patches w/ multiple small dark macules/papules
Congenital melanocytic nevi-time frame for risk developing melanoma
- Small (20cm) high during 1st year of life
Congenital melanocytic nevi- large lesions
- dermatomal distribution “cape-like” “stocking” -lesions over scalp, midline neck, spine ass w/ neurocutaneous melanosis (spina bifida, meningomyelocele, Dandy-Walker malformation)
Nevus Ota
unilateral, speckled areas bluish-gray discoloration on face - need yearly optho exams & skin exam for melanoma
Crowe sign
-small, grouped, freckled like, cafe-au-lait spots 1-4mm in axilla/groin -ass w/ Neurofibromatosis type 1
Ichthyoses- Dominant vs Recessive vs lamellar
X-linked - at birth or 1st weeks - more pronounced, darker, palms/soles unaffected - males undescended testes w/ underdeveloped penis/scrotum Lamellar - Newborn -Large, generalized plate-like scaling minimal no redness Dominant (vulgaris) - after 3 months - fine, white scales no redness w/ thickening palms,soles
Type 1 Neurofibromatosis
- cafe-au-lait - neurofibromas
Tuberous sclerosis
-facial angiofibromas -ash-leaf spots -shagreen patch -periungual fibromas
Peutz-Jeghers Sy
- GI polyps -hyperpigmented macules of mucosa/perioral plus fingers toes
Incontinenta Pigmenti
- 1st few week of life- Patterned blistering followed lines Blaschko esp extremities
- 1st weeks-months - verrucous papules
- months-yrs- hyperpigmented linear swirl patches
Ass w/ - cicatricial alopecia & delayed eruption & abnormal teeth
Hypohidrotic Ectodermal Dysplasia
- X-linked recessive - Facies: frontal bossing, thin upper lip, small chin, prominent ears, pegged teeth , periorbital wrinkling - No secretions- skin, nose, eyes or mouth
Acquired Melanocytic Nevi
- Normal nevi
- Junctional nevi- along dermal-epidermal jun & are flat & brown —>Compound- are raised pink/brown —>Intradermal- in dermis & are dome shaped
Polyglandular deficiency
- AR - vitiligo plus endocrine abnor (DM, Grave dz, hypo/hyperthyroi, etc.)
Lichen striatus
-linear group small, violaceous, flesh-colored or hypopigmented papules -most common arms/legs -self resolve
Location of atopic dermatitis infants vs. older children
why avoid PO steroids in atopic dermatitis
- increase likelihood of rebound flares
Isotretinoin SE
- pseudotumor cerebri
- depression, psychosis
- pancreatitis with hypertriglyceridemia
- hearing loss & night vision loss
- skeletal abnormalities
Pityriasis alba
areas of hypopigmentation w/ fine scale on cheecks & extensor surface
-common pt w/ atopic dermatitis
