Inflammatory Skin Dz, Vitamin Def,Skin Inf, Blisters/Round Lesions

Question 1

Guttate psoriasis

Answer 1

-many small, scaly papules & plques on face/trunk/proximal extremities

Question 2

? is Koebner phenomenon

Answer 2

• outbreak in area of abrasion

Question 3

Erythrodermic psoriasis

Answer 3

• entire surface skin becomes red, warm & scaly
• Ass w/ dehydration, hypoalb, hypo/hyperthermia, anemia chronic dz
  TX- acitretin

Question 4

Pustular psoriasis

Answer 4

-psoritic pustular lakes of pus
2 forms
-localized- ONLY palms/soles w/ ass DIP arthritis
-generalized
TX- acitretin, MTX (esp if ass w/ arthritis)

Question 5

Nail changes ass w/ psoriasis

Answer 5

• pitted nails w/ onycholysis ( separation distal nail from nail bed)

Question 6

Neonatal lupus

Answer 6

• 2nd to Ro antigen crossing placenta
• EITHER congenital heart block OR cutenous lupus
• DX- anti-RO & anti-La antibodies

Question 7

Sarcoidodis

Answer 7

• noncaseating granulomatous dz of lung/lymph nodes,eyes, skin
• ass w/ erythema nodosum
• TX-topical steroids, MTX

Question 8

Lupus pernio

Answer 8

• type sarcoidosis

- purple lesion tip nose/earlobes to large purple nodules/tumors face/fingers

Question 9

Erythema nodosum

Answer 9

• inflammation fat presents as red, very painful, warm nodules usually shin
• ass w/ OCP & IBD/TB/Sarcoidosis

Question 10

Dermatomyositis

Answer 10

• SX- periorbital heliotropic rash , Grotton papules over knuckels
• TX- glucocorticoids

Question 11

Older pt Dermatomyositis may incate ____

Answer 11

cancer usually GI

Question 12

Zinc deficiency

Answer 12

SX- red, irritant, eczemoid rash of nasolabial folds, perioral, extensor surfaces & perineum/scrotum

Question 13

Erythrasma SX, DX

Answer 13

• Well-defined, reddish lesion w/ some slight scaling axilla,groin & toe webs
  DX- fluoresce bright red w/ Wood’s lamp

Question 14

Erysipelas

Answer 14

• Explosive, superficial cellulitis confined to dermis
• Clear demarcation of swelling/redness
• Ass w/ Strep

Question 15

Necrotizing fasciitis

Answer 15

• Deep cellulitis of subcutanous fat & fascia
• No distinc borders
• Ass w/ Strep

Question 16

Bullous impetigo

Answer 16

• large, loose bullae –> rupture quickly leaving shallow erosions
• toxin producing S. aureus

Question 17

Neisseria gonorrhea

Answer 17

• few (<12) papular petechial rash that become pustules

- usually around joint

Question 18

Pseudomonas

Answer 18

• small necrotic papules

- in ill, neutropenic pt can evolve to ecthyma gangrenosum (necrotic ulcer w/ erythematous rim)

Question 19

Rickettsial

Answer 19

• distribution from peripheral to central

- type macular–> petechial –> purpuric

Question 20

Phemphigus vulgaris

Answer 20

• antibody against epidermal desmoglein proteins

- TX- high-dose glucocorticoids

Question 21

Nikolsky sign

Answer 21

• epidermal sliding w/ digital pressure on the skin

- indicates acantholysis ( separation epidermal cells from each other 2nd decrease cohesion)

Question 22

Porphyria cutanea tarda SX, DX

Answer 22

SX:

• hyperpigmentation & tense blisters in sun-exposed areas
• increase facial hair
• Induce by ingestion estrogen or alcohol
• DX- increase urinary coproporphyrins & uroporphyrins

Question 23

Drugs that cause photosensitive

Answer 23

-Tetracycline, sulfonamides & quinolones

Question 24

Erythema multiforme minor

Answer 24

• <2 mucous membranes

- Ass w/ herpes simplex virus

Question 25

Erythema multiforme major

Answer 25

• 2 or more mucous membranes

- Ass w/ mycoplasma inf

Question 26

Pityriasis rosea

Answer 26

• small, oval, pruritic papulosquamous lesion with long axis parallel to skin fold & rib lines in Christmas tree
• preceded by herald patch by 1-2 weeks