Neoadjuvant Therapy Flashcards
1
Q
What is the advantage of using neo adjuvant chemotherapy over adjuvant chemotherapy?
A
Downstaging with some being pathologically complete response (pCR)
Increased rates of breast conserving therapy
No difference in overall survival and disease free survival
2
Q
What factors are associated with pathologically complete response for neoadjuvant therapy for breast cancer?
A
Age < 40 Size < 2cm Ductal histology High grade High Ki67 Oestrogen -ER negative Triple negative HER2 positive
