Nematodes Flashcards
memorize
Tissue nematodes
Wuchereria bancrofti Loa loa
Wuchereria bancrofti
vector-culex mosquito microfilaria have nocturnal periodicity
cycle
adults mate and females produce microfilaria .They are picked by mosquito during the night-migrate to the midgut-thoracic muscles -mature fromL1-L3(filariform)-migrate to the proboscis.-During feeding the filariform are transfered to human skin-get into lymph vessles -mature-mate produce microfilaria.
manifestations
lymph edema-blockage of lymph vessels by microfilaria elephantiasis-poisoning
Podoconiosis
non-filarial elephantiasis -does not involvr microfilaria-minerals penetrate skin and block vessels.
Dracunculus medinensis(guinea worm)
pattern involves cyclop.Transmission is by drinking contaminated water .male dies after mating
life cycle
contaminated water containing cyclop which has L3 is ingested-larva is released in the stomach-penetrates intestinal wall and travels to the subcutaneous tissue-mature into adults-mate-male dies-female travels to limbs -causes blisters -protrudes and discharges the microfilaria-swims looking for cyclop-molts twice inside cyclop awaiting ingestion.
manifestation
loss of eyesight,blisterd,ulceration of wound;allergic reaction.
diagnosis
rise in eosinophil titre
Loa loa(thread worm)
infection-loiasis also called eyeworm causes calabar swellings on skin vector-mango/deer fly from species Chrysops dimidiata. has a painful bite because it has a blunt mouth sheathed microfilaria with diurnal periodicity
manifestations
calabar swellings,allerguc reaction to metabolic byproduct,pain,retinopathy,lymphadenitis.
Onchocerca vulvus
vector-black fly -simulium damnosum.Diurnal periodicity.
clinical manifestations
fibrous nodules on skin surfaces which form hyper and hypopigmentation after a while. skin wrinkles and thickens appears like skin of leopard or lizard. causes elephantiasis of the eye which leads to blindness.
Askaris lumbricoides(round worm)
male has a curled tail with some protruding spicules for copulationwith straight posterior tail. Transmission-ingestion of food containing eggs invades the lungs. fertalize into infective stage in the soil.
Hookworms
two species-Necatur americanus and ancylostoma duodenale. unembryonated eggs released -embroynated in warm moist soil. rhabditiform larva hatches in warm moist sandy soil to L1