Neil Keddie- Lecture 1 Intro to Organic Reaction Mechanisms

Question 1

What is the definition of Ann exergonic reaction?

Answer 1

ΔG is -ve

Question 2

What is the definition of an endergonic reaction?

Answer 2

ΔG is positive

Question 3

How does ΔG relate to the equilibrium constant?

Answer 3

ΔG= -RTlnK

Question 4

What does thermodynamics tell us?

Answer 4

How far a reaction will go

Question 5

What does kinetics tell us?

Answer 5

How fast a reaction will go

Question 6

Describe the transition state.

Answer 6

The structure present at the energy machine.
It exists for less than a molecular vibration and cannot be observed.
It contains only partial bonds or charges. It is typically drawn in square brackets with a double dagger.

Question 7

What is the Hammond Postulate?

Answer 7

“A transition state linking two pints in a potential energy surface resembles the nearest stable species.”

Question 8

Describe the transition state in an exergonic reaction.

Answer 8

Early reactant like transition state

Question 9

Describe the transition state in an endergonic reaction.

Answer 9

Late product line transition state

Question 10

Describe a reaction intermediate.

Answer 10

A species briefly created in a multi step reaction.
It has its own activation energy and transition state.
It’s a localised energy minima which can be isolated (with difficulty) and observed spectroscopically.