Need to Remember

Question 1

What amino acids absorb UV?

Answer 1

Phe
Tyr
Trp

SAME AS Chymotrypsin

Question 2

Monoubiquitination regulates …

Answer 2

histones

Question 3

Multiubiquitination regulates …

Answer 3

endocytosis

Question 4

What are the 2 endopeptidases?

Answer 4

1. trypsin
2. chymotrypsin

Question 5

What amino acid doesn’t have a chiral carbon?

Answer 5

glycine

Question 6

What is the structure of collagen?

Answer 6

triple helix

Question 7

Does collagen have left or right handed helix?

Answer 7

left (forms a right supercoil)

Question 8

What is the structure of keratin?

Answer 8

2 antiparallel dimers form a tetramer

Question 9

Does Keratin have a right handed or left handed helix?

Answer 9

right (forms a left supercoil)

Question 10

Jelly rolls beta strands follow the ______ of the barrel

Answer 10

surface

Question 11

What amino acids have hydroxyl groups?

Answer 11

Ser
Thr
Tyr

PHOSPHORYLATION

Question 12

What amino acids have amine groups?

Answer 12

Arg
His
Lys

BASIC AMINO ACIDS

Question 13

What amino acid has thiol groups?

Answer 13

Cys

Question 14

What amino acids have carboxylate groups?

Answer 14

Aspartic acid
Glutamic acid

Question 15

Why do tertiary structures have stability?

Answer 15

surface/volume ratio increases favorable protein-protein interactions rate

Question 16

Why do tertiary structures have efficiency?

Answer 16

large proteins are synthesized in smaller chunks

Question 17

Why do tertiary structures have assembly?

Answer 17

catalytic sites are made

Question 18

Why do tertiary structures have regulation?

Answer 18

protein protein interactions

Question 19

What are the 4 proteases that target functional groups?

Answer 19

Cysteine protease
Serine protease
Aspartic acid protease
Zinc metalloprotease

Question 20

Where is a left handed helix located on a Ramachndran map?

Answer 20

+60 +60 (top right)

Question 21

Where is the alpha carbon located?

Answer 21

connected to the NH and carbon with COO on it

Question 22

T/F? Due to its partial double bond characteristic, the peptide bond does not freely rotate.

Answer 22

true

Question 23

Are proteins more or less soluble at the isoelectic point?

Answer 23

less

Question 24

What aid in platelet formation?

Answer 24

fibrin

Question 25

Is alpha or beta keratin stretched?

Answer 25

beta

Question 26

What is horseshoes made if?

Answer 26

alpha and beta

Question 27

What does polyubiquitantion control?

Answer 27

protesomal degradation

Question 28

How many beta strands make up a jelly roll?

Answer 28

8