Necrotising periodontitis Flashcards
Describe the terms necrotising gingivitis, necrotising periodontitis and necrotising stomatitis
- The three necrotizing diseases appear to represent various stages of the same disease process
- A distinction between the different manifestations has not always been made in the literature
- Hence, necrotizing periodontal disease is an umbrella term for the diseases.
State the synonyms for necrotising gingivitis, necrotising periodontitis and necrotising stomatitis
Necrotising gingivitis:
• Trench mouth
• ANUG/ NUG
Necrotising periodontitis:
• Necrotising Ulcerative Periodontitis (NUP)
Necrotising stomatitis:
• NOMA
• Gangrenous stomatitis
State the microflora involved in the pathogenesis of necrotising periodontal diseases
- Treponema spp.
- Selenomonas spp.
- Fusobacterium spp.
- Prevotella intermedia
State the causes of necrotising periodontal diseases (general) (5)
Caused by bacterial infection in patients with specific underlying risk factors: • Poor oral hygiene • Smoking • Stress • Poor nutrition • Compromised immune status [e.g., HIV])
Explain why necrotising periodontal diseases are important and the use of the descriptor term ‘acute’
- Although the prevalence of necrotizing periodontal diseases (NPD) is low, it’s important because it is a severe condition associated with dental biofilm which causes rapid destruction
- Although the necrotizing diseases often run an acute rapidly destructive course, the term acute has not been included in the diagnoses since 1999.
Does ulcerative gingivitis cause loss of periodontal attachment?
• The term “gingivitis” is used for lesions only involving gingival tissue and characterized by no loss of periodontal attachment.
Describe the clinical features of Necrotizing Gingivitis
- Small, grey, ulcerative lesions at tips of interdental papillae
- Spreads to gingival margins to create cratered lesions
- Greyish- white pseudomembrane may cover affected areas
Describe the signs (3) and symptoms (4) of Necrotizing Gingivitis
Signs:
• Spontaneous gingival bleeding
• Burning sensation in mouth
• Heavy plaque deposits
Can spread to underlying periodontal tissues
Symptoms: • lymphadenopathy (lymph nodes abnormal in size, consistency and number) • Fever • foul mouth odour • malaise
Describe the microbiology of Necrotizing Gingivitis
Spirochetes • Fusobacterium • Prevotella intermedia • Treponema • Selenomonas
Describe the clinical features of Necrotizing Periodontitis (5)
- Ulceration of the gingival margin
- Fibrin deposits at sites with characteristically decapitated gingival papillae
- Extensive necrosis of gingiva
- Exposure of the marginal alveolar bone and destruction of the bone
- Extensive attachment loss (doesn’t necessarily cause deep perio pockets)
Describe the signs and symptoms of Necrotizing Periodontitis (2)
Signs:
• Severe pain
• 50% of sites show spontaneous bleeding
Describe the microbiology of Necrotizing Periodontitis
○ Spirochetes-Borellia vincentii ○ Prevtella intermedia ○ Treponema species ○ Selenomonas species ○ Fusobacterium species ○ Vincent vicella
Understand when the three terms are used in diagnosis
Necrotising gingivitis:
• Used for lesions only involving gingival tissue and characterized by no loss of periodontal attachment
Necrotising periodontitis:
• Characterised by loss of attachment
Necrotising stomatitis:
• Ulcers extend 1cm from the gingival margin. Including tissue beyond the mucogingival junction
Discuss why necrotising periodontitis is considered a separate disease entity from periodontitis (4)
- It has a distinct pathophysiology characterized by prominent bacterial invasion and ulceration of epithelium
- Involves rapid and excessive destruction of the marginal soft tissue resulting in soft and hard tissue defects
- Has prominent symptoms
- Rapid resolution in response to specific antimicrobial treatment
Discuss the causes/ risk factors for Necrotizing Gingivitis (12)
- Related to psychological stress & systemic disease
- Stress-related epinephrine may cause localized ischemia, predisposing gingiva to Necrotizing Gingivitis
- Corticosteroids may alter lymphocyte ratios and cause decreased neutrophil chemotaxis and phagocytic response
- Immunocompromised status (E.g. AIDS & infectious mononucleosis)
- Poor eating habits of young adults (college students); low protein intake
- Caucasian background
- Local trauma
- Inadequate sleep
- Recent illness
- Poor oral hygiene
- Alcohol use
- Smoking
Discuss the risk factors for Necrotizing Periodontitis (5)
- Immunosuppression
- Malnutrition
- Following necrotising gingivitis
- Patients younger than those who experience normal periodontitis
- May present in area of pre-existing periodontitis or as sequela to Necrotizing Gingivitis
Discuss the appropriate treatment for Necrotizing Gingivitis
- First appointment
- 2nd appointment
- 3rd appointment
- Post treatment/ revaluation
1st Appointment-
• Supra gingival scale only
• OHI
• Removal of bacteria
• Chlorhexidine rinses, warm saltwater or diluted hydrogen peroxide
• Antibiotics are useful adjunct (metronidazole)
2nd appointment – (1-2 days after)
• Removal of bacteria through debridement/ scaling but under LA
3nd appointment – (5 days after the 2nd visit)
• Debridement but under LA
• OHE
Post-treatment: Revaluation (1 month)
• Oral hygiene instructions / education
• Identification and resolution of predisposing factors
• Supportive therapy (E.g. rest, nutritious diet, appropriate fluid intake)
Discuss the prognosis for Necrotizing Gingivitis
• Quick resolution after removal of bacterial challenge
Discuss the appropriate treatment for Necrotizing Periodontitis. Mention:
- Initial treatment goals
- Considerations for the HIV patient
- Post- treatment
Initial treatment
• Remove bacteria
• Mechanical debridement
• 5 mL Nystatin rinse for HIV-positive patients
• Given LA or topical with NSAIDs
• Systemic antibiotics
• Removal of underlying influence (E.g. immunosuppression, malnutrition)
Post-treatment:
• Oral hygiene instructions / education
• Saline rinses can help to speed resolution
• Oral rinses with a hydrogen peroxide 3% solution may help
• Chlorhexidine 0.12% oral rinse 15 mL
Discuss the prognosis for Necrotizing Periodontitis
- Responds well to treatment
* However, loss of attachment and alveolar bone