Necrosis Flashcards
1
Q
Coagulative
A
Ischemia/infarcts in moist tissues
due to ischemia or infarction
proteins denature–>enzymatic degradation
2
Q
Liquefactive
A
Bacterial abscesses
Neutrophils release lysosomal enzymes that digest the tissue
enzymatic degradation–>proteins denature
3
Q
Caseous
A
TB, systemic fungi
Macrophages wall off the infecting microorganism–>granular debris
4
Q
Fat
A
enzymatic: acute pancreatitis
nonenzymatic: traumatic
Damaged cells release lipase to break down triglycerides, liberating fatty acids to bind calcium–>saponification
5
Q
Fibrinoid
A
immune reactions in vessels, preeclampsia, malignant hypertension
Immune complexes combine with fibrin –>vessel wall damage
6
Q
Gangrenous
A
distal extremity and GI tract, after chronic ischemia
Dry: ischemia
Wet: superinfection
