Neck lumps pathology Flashcards
What is a branchial cyst?
-Original theory: branchial pouch remnant
-Now: Stratified squamous incorporated into cervical lymph tissue
Originally thought to be a branchial pouch remnant
However, the general consensus has now changed and branchial cysts are thought to be
stratified squamous epithelium incorporated into cervical lymph tissue
Where are branchial cysts most commonly found?
-Anterior to upper 1/3rd of the sternocleidomastoid muscle (SCM)
-anterior triangle of the neck
-2% are bilateral
When do branchial cysts present?
Most commonly seen in the 2nd - 3rd decade of life
How would you describe branchial cyst?
-Firm, smooth swellings
-Can become infected
How would you investigate a patient with a branchial cyst?
Fine needle aspirate (FNA)
This can be carried out in the clinic or under ultrasound guidance
MRI / CT neck to assess the extent of the mass and its relationship to major vessels
Describe aspirate of branchial cyst
The aspirate is typically straw coloured and rich in cholesterol, although pus may be present
when infected
How would you treat a branchial cyst?
Excision. Not to be undertaken lightly!
This must be carried out when the cyst is not infected as this will increase the risk of rupture
and recurrence
The next patient has been referred as they have a midline neck swelling that moves when they
protrude their tongue
What is the diagnosis?
Thyroglossal cyst
What is a thryoglossal cyst?
When do they present?
How do they present?
-Remnant of thyroglossal duct
-Presents in 1st decade
-Elevate when tongue is protruded
It is a remnant of the thryoglossal duct which represents the embryological path of the thyroid gland from its origin at the base of the tongue (foramen caecum)
The thyroglossal duct is usually obliterated after the descent of the thyroid gland
40% present in 1st decade with mean age of presentation 4 years old. However, they can be
seen much later into adult life
They will elevate when the tongue is protruded due to the embryological origin at the base of the tongue
Can enlarge rapidly if become infected
Are thyroglossal cysts always found in the midline?
No.
80 - 90% are in the midline
They can lie anywhere from the chin to the 2nd tracheal ring and be slightly off the midline
What other diagnoses should you consider as differential for swelling in midline?
Dermoid cyst
Lymph node
Sebaceous cyst
Thyroid nodule
What is the name of the operation to excise a thyroglossal cyst?
Sistrunk’s procedure
The thyroglossal duct surrounds the body of the hyoid bone and it is removed along with the
cyst
If the hyoid bone is not removed then recurrence rate is > 80%
The excised thyroglossal cyst is sent for histology. What will the cyst contain?
Most likely lymphoid tissue
It may contain ectopic thyroid tissue and it is essential to fully investigate the lump prior to surgery as the cyst may be the only functioning thyroid tissue that a patient has.
Ultrasound is used to assess the mass but also to look for a normal thyroid gland
What is a dermoid cyst?
It is an epithelial lined cyst that lies deep to the skin
They can be:
Congenital: result from inclusion of the epidermis along fusion lines of skin dermatomes
or
Acquired: usually secondary to an injury and skin forced into a wound
What are the most common sites for congenital dermoid cyst?
Medial and lateral aspects of the eyebrows
Midline of nose
Midline of neck and trunk
How would you treat a dermoid cyst?
Excision but with caution as congenital dermoid cysts may communicate with deep structures
Therefore pre-operative imaging may be required
What is a sebaceous cyst?
Epidermoid or pilar cyst
The term sebaceous cyst is not fully correct. Used to describe below:
The correct terminology is either:
An epidermoid cyst: cyst that arises from epidermis
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or
A pilar cyst: cyst that arises from hair follicles
What are the classical clinical features of sebaceous cyst?
Smooth lumps attached to the skin and therefore do not move independently
Often firm consistency
May have a punctum, that may discharge
Can be erythematous and painful when infected.
What are the most common sites that sebaceous cysts occur?
Scalp
Face
Neck
Trunk
What is the treatment for sebaceous cyst?
Most commonly excised with overlying skin as it contains a punctum
What is a lipoma?
It is benign collection of fat cells that is typically found in the subcutaneous layer of skin
What are the clinical features of a lipoma?
Soft and slightly mobile
Very slow growing
Most common sites are shoulders and trunk
They are not found on palms or soles
What is the treatment of lipomas?
Often no treatment
or
Excision (often for cosmetic reasons)
The next patient is an emergency referral from a GP with an acute left side submandibular
swelling
The swelling has arisen over the past 24 hours, it is warm, red and very painful. It was
preceded by 2 days of dental pain
What is the most likely diagnosis of this neck swelling?
Submandibular abscess secondary to a dental cause