Melanoma left over

Question 1

What is the definition of a melanoma?

Answer 1

-Malignant neoplasm of melanocytes (melanin producing cells) mainly arising in the skin

Other sites: nasal cavities, retina, GI mucosa

Question 1

Difference between melanoma and SCC?

Answer 1

-SCC superficial layers, melanoma deeper layer (granulosum)
-continuous vs intermittent sun exposure
-Arises in sun exposed areas vs anywhere
-Appears as red bump/scaly patch/non healing sore vs irregular mole
-Better vs poorer prognosis
-Metastasis less vs more common

Question 2

Difference between BCC and SCC

Answer 2

-Spreads less vs more commonly
-Stratum basale vs more superfiical layers
-more vs less common
-Raised pearly edges vs thickened exophytic growth with necrotic core

Question 3

What to do to ensure adequate margins

Answer 3

Frozen secion
-Moh’s surgery

Question 4

Post excision the patient developed regional lymphadenopathy, management?

Answer 4

-FNAC
-Staging CT

Question 5

How would you manage PE?

Answer 5

-CTPA
-SC LMWH if haemodynamically stable
-Thrombolysis or embolectomy for massive PE

Question 6

What is epitheloid melanoma?

Answer 6

-Melanoma cells can be categorised into 2 major cell types: epithelioid and spindle cell
-Epithelioid are large and round with abundant eosinophilic cytoplasm, prominent vesicular nuclei and large nucleoli
-They most commonly arise in superficial spreading and nodular melanomas

Question 7

What is a satellyte lesion?

Answer 7

-Form of local spread of malignant melanoma by contiguity and continuity leading to pigment spreading to surrounding area. FOund within 2cm of primary tumour