NCLEX Pharm Flashcards
Feverfew Interacts with:
aspirin, warfarin, clopidogrel – caution related to blood clotting
Psyllium
bulk-forming laxative; esp used in diverticulitis; ae: esophageal obstruction
Ciprofloxacin
UTIs; ae: achilles tendon rupture; intx with warfarin!
Diazepam antidote
Flumazenil
What should be taken with iron to increase absorption
Vitamin C
Neostigmine
Myasthenia Gravis drug.
Ae: salivation, fasciculation, bowel cramps, diarrhea,
Intx: antibiotics – neomycin
Diltiazem
Calcium Channel Blocker
anti hypertensive
CYP450!
ae: edema, fatigue, nausea, hypotension
Amphotericin B
anti-fungal for severe systemic fungal infections (not thrush); cardiac issues possible; careful with dosing; IV only.
Ae: fever, weight loss, hypotension, tachypnea, N/V, diarrhea, anemia, h/a, decreased renal function.
Tolerance improved with: aspirin, acetaminophen, antihistamine, antiemetics,
Baclofen
Muscle relaxant, spasticity – usually used for MS; may also help restore function in pt w/ spinal cord injuries
gradual increase of dose
AE: drowsiness, dizziness, weakness, fatigue, confusion, h/a, nausea
withdrawal possible – discontinue gradually
tDAP
give first dose at 2 months; then 4m, 6m
What to drink with furosemide?
milk!
Clozapine
Treats schizophrenia,
2nd generation antipsychotic = less EPS symptoms but metabolic syndrome likely (weight gain, hyperlipidemia, etc)
Trimethoprim/Sulfamethoxazole
Antibiotic - UTI, ear infection, bronchitis
Ae: N/v, tinnitus, dizziness, insomnia
teratogenic thrombocytopenia C Diff agranulocytosis
reduce dose in pt with impaired renal function
dilute in 5% dextrose in water
Drug intx: diuretics, methotrexate, cyclosporine,
Amitriptyline
tricyclic antidepressant, improves mood, anticholinergic, orthostatic hypotension.
don’t stop taking abruptly.
Tranylcypromine
MAOIs
No: tyramine, CYP450
Stop for 2 wk before taking other drugs
AE: weight gain, constipation, hypotension
Hypertensive crisis aeb vomiting d/t bad interaction