nature of disease and purpose of therapy Flashcards

1
Q

are health and disease hard to define

A

yes

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2
Q

why are health and disease hard to define

A

environment and society
health is continuous

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3
Q

health

A

state of complete mental , physical and social well-being and not just the mere absence of
sickness or infirmity
age, culture and personal responsibility also play a part

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4
Q

disease

A

a condition that interferes or alters the normal state of the organisms usually characterised by the abnormal functioning of one or more of the hosts systems, parts or organs.

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5
Q

naturalistic view

A

A condition which alters or interferes with the normal state of an organism and is usually characterised by the abnormal functioning of one or more of the host’s systems, parts or organs

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6
Q

normative view

A

any condition that an individual or society find harmful

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7
Q

disease definition 2

A

States of affairs are called diseases when they are due to physiological or psychological processes that typically causes states of disability, pain or deformity and are generally held to be below acceptable physiological or psychological norms

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8
Q

disease definition 3

A

deviation from normality, cause signs and symptoms

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9
Q

three factors of diseases

A

DISVALUE (NORMATIVE VIEW)
PHENOMENOLOGY (NATURALISTIC VIEW)
AETIOLOGY (CAUSE)

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10
Q

aim of therapeutic intervention

A

is to limit the effect of disvalue

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11
Q

disvalue => mobility

A

the presence of symptoms

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12
Q

disvalue => prognosis

A

likelihood of increased mobility or premature death

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13
Q

lifestyle drug

A

those medications taken solely to increase personal life quality and to attain a current psychosocial beauty ideal, without a medical need for treatment

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14
Q

what is the most common drug target

A

receptors

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15
Q

what are receptors

A

proteins sitting in plasma

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16
Q

why is it hard to get drugs into cells

A

very lipophilic hard to get drug through cell membrane

17
Q

order of drug action (gene to population)

A

gene
protein - most drugs start here
cell
tissue
physiological system
individual
family
society

18
Q

drug likeness

A

the physiochemical properties of a new chemical entity can help determine if it will be a good drug

19
Q

criteria of good drug likeness

A

liberation
absorption
distribution
metabolism
excretion

20
Q

toxicity

A

is the degree to which a substance can damage an organism

21
Q

how can toxicity manifest

A

side effect
adverse reaction
death

22
Q

how may toxicity occur

A

with overdose of a medication accumulation of the drug in the body , inability of the body to eliminate the drug

23
Q

properties of an ideal drug

A

produced the desired effect
easy to administrate
minimal dose and frequency
minimal side effects
timely elimination
ease to source
inexpensive to manufacture
stable