Nature, Nurture and the genome Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

What are some features of predominantly genetic diseases?

A

Rare, simple genetics, unifactorial, high recurrence rate within families

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are some features of mostly-environmental human diseases?

A

Common, with complex genetics, multifactorial, and low recurrence rate within families

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are some tools used to gain evidence about heritability (4)

A

Familial risk, twin studies, adoption studies, and population & migration studies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is polygenic inheritance?

A

The inheritance and expression of a phenotype being determined by many genes at different loci. Each allele has a small addative effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are multifactorial disorders?

A

Diseases which need the interaction of environmental and genetic factors to become manifest.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Define penetrance

A

Chance a genotype results in associated phenotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are mendel’s two laws?

A

Law of segregation: Members of each pair of genes seperate when gametes form
Law of independent assortment: 2+ gene pairs are segregated independently (a bit wrong)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What breaks the law of independent assortment?

A

Gene linkage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is homologous recombination also known as?

A

Crossing over

How well did you know this?
1
Not at all
2
3
4
5
Perfectly