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Obs Gynae > Natural Methods Of Conception > Flashcards

Natural Methods Of Conception Flashcards

1
Q

What is the time required to reach the site of fertilisation for an ejaculated sperm

A

30 min

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2
Q

Capacitation starts where
Where does major part of capacitance takes place
Duration
What does a sperm achieve after capacitance

A

Cervix
Fallopian tube
7 hrs
Hypermotility (full maturity)

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3
Q

Main enzyme in acrosomal reaction

A

Hyaluronidase

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4
Q

Name the receptor of sperm on zona pellucida

A

ZPGP-3 (ZP Glycoprotein)

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5
Q

Zona pellucida breaks down due to which action of sperm

A

Hypermotility

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6
Q

Zygote is formed by fusion of what

A

Female pronucleus + male pronucleus = conceptus /zygote

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7
Q

Gene responsible for fusion of male and female pronucleus

A

FERTILIN (new discovery)

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8
Q

Conceptus stays in Fallopian tube for how much time

A

3 days after fertilisation

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9
Q

Conceptus enters the uterine cavity at what time

A

On 4th day after fertilisation

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10
Q

Conceptus enters uterine cavity in which form
In what cell stage it enters the uterine cavity
Morula is which cell stage
1. 8
2. 10
3. 14
4. 16

A

MORULA (8-16 cell stage)
8 cell
4. 16 Cell stage

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11
Q

Implantation begins on which Day and is completed by which day

A

Begins on 6th day and completed by 10th day

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12
Q

Phases of implantation and transmitter required in that stage

A

3 phases : transmitters required
Apposition:SELECTIN
Adhesion:INTEGRIN
Invasion:MATRIX METALLOPROTENASES

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13
Q

Implantation happens which stage

And on what day

A

Blastocyst stage

Day 5

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14
Q

Function of zona pellucida

When is zona pellucida lost

A

Prevention of polyspermy
*Ca ion responsible
Just before implanatation or day 5

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15
Q

Terms for the following

  1. Endometrium of pregnant female
  2. Decidua below conceptus
  3. Decidua above conceptus
  4. The remaining rest of the decidua
A
  1. Endometrium of pregnant female : decidua
  2. Decidua below conceptus : basalis
  3. Decidua above conceptus : capsularis
  4. The remaining : peritalis
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16
Q

At what weeks the capsularis and peritalis fuse and what is it known after fusion

A

Fusion happens at 14-16 weeks

After fusion it is called as decidua Vera

17
Q

Superfetation

A

If before fusion of capsularis and peritalis another conceptus attaches it is known as superfetation
Theoretically twinning can happen up to 16 weeks (since capsularis and peritalis fuses at 14-16 weeks) but it is not documented in humans

18
Q

Embryonic phase last up to how many days post fertilisation and from L.M.P

A

8 weeks post fertilisation
10 weeks from L.M.P
After that it is called as foetus

19
Q

Invasion of trophoblast is absent in which condition

A

Pre-eclampsia

20
Q

Fetal membrane is derived from
Name them
New concept related to aminon

A 
Trophoblast 
1. amnion
2. Chorion 
3. yolk sac 
4. allantois
Amnion developed from FETAL ECTODERM 
It is inner most fetal membrane 
Entire tensile strength of fetal membrane 
It is avascular
21
Q

What are the types of chorion

A

Chorion laeve - it fuses with amnion

Chorion fundosum - give rise to placenta

22
Q

What is allantois

A

It is a diverticulum from the hind gut that grows into connecting stalk
It gives rise to umbilical vessels

23
Q

The 1st area where fetal hematopoiesis begins is

A

Yolk sac

24
Q

Primitive haemoglobions are formed where

A

Yolk sac

  1. Gover 1
  2. Gover 2
  3. Portland
    - not HbF
25
Q

Extramedullary site for Hb production

A

Liver after > 6 weeks

26
Q

Which of the following is true

  1. HbF are bigger in size
  2. HbF are shorter in lifespan
  3. HbF Made up of : alpha 2 gamma 2
  4. HbF Has lesser affinity for O2
  5. It is resistant to both acid and alkaline denaturation
A

1,2,3,5 are true
HbF has higher affinity for O2 as compared to other Hb therefore fetal Hb dissociation lies left to maternal dissociation curve b/c of less 2,3-DPG and carbonic anhydrase

27
Q

How does one calculate the dose of anti-D to be given in Rh -ive pregnanat female

A

By acid denaturation
KB Test (Kleihauer betke test)- citric and PO4 buffer
quantitative test

28
Q

Test to differentiate fetal blood cell from mother’s blood

A

K B Test (Kleihauer betke test)

Quantitative test

29
Q

What is the test used by pediatrician’s to find out mom’s /baby’s blood
Other test used

A 
Alkaline denaturation test - APT test 
Qualitative test 
It is a bed side test 
Mom’s blood - change colour (-ive)
Baby’s blood - colour resistant (+ive)
Other test - singer’s alkali denaturation test
30
Q

switch over to adult Hb begins at

And completes at

A

Begins at 36 weeks

Complete at birth

31
Q

Hb of baby at birth
At birth :
At 6 months :

A

18g%
At birth :75-80% of total Hb is HbF
At 6 months : HbF <1%

Obs Gynae (7 decks)

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