Nasopharynx Flashcards
What is Rhinitis?
Inflammation of the nasal mucosa.
What is the nasal mucosa lined with?
Respiratory type epithelium
What is the most common cause of Rhinitis?
Adenovirus
What does Rhinitis present with?
-Sneezing
-Congestion
-Runny nose
(common cold)
What is a common subtype of Rhinitis? What type of hypersensitivity is it?
Allergic rhinitis
Type I hypersensitivity
What is an example of allergic rhinitis?
Pollen
What conditions is Allergic Rhinitis associated with?
Asthma & Eczema (Atopic disorders)
What histology characterizes Allergic Rhinitis?
An inflammatory infiltrate with eosinophils
What is a Nasal Polyp?
Protrusion of edematous, inflamed nasal mucosa
What is a Nasal Polyp usually secondary to?
Repeated bouts of rhinitis
In what two conditions does Nasal Polyp often occur?
- Cystic fibrosis
2. Aspirin-intolerant asthma
If you encounter a child with nasal polyps, what should you check for?
Cystic Fibrosis
What triad characterizes Aspirin-intolerant asthma?
- Asthma
- Aspirin-induced bronchospasms
- Nasal Polyps
What is Aspirin-intolerant asthma seen in?
10% of asthmatic adults
What does Angiofibroma stand for?
Angio = Blood vessel fibr = fibrous tissue oma = mass
What is an Angiofibroma?
Benign tumor of nasal mucosa composed of large blood vessels and fibrous tissue
What population is Angiofibroma classically seen in?
Classically seen in adolescent males (extremely rare in females)
What does Angiofibroma classically present with?
Presents with profuse epistaxis
What is carcinoma?
A cancer that develops from epithelial cells
What is Nasopharyngeal Carcinoma?
Malignant tumor of nasopharyngeal epithelium
What condition is Nasopharyngeal Carcinoma associated with?
EBV (Epstein-Barr Virus)
What populations is Nasopharyngeal Carcinoma classically seen in?
- African children
- Chinese adults
What is seen on biopsy of Nasopharyngeal Carcinoma?
Pleomorphic Keratin-Positive epithelial cells (poorly differentiated squamous cell carcinoma) in a background of lymphocytes
What does Nasopharyngeal Carcinoma often present with?
Involvement of cervical lymph nodes
Chinese adults w/ cervical lymph nodes. You do a biopsy. What condition is it?
Nasopharyngeal Carcinoma