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Uworld NAPLEX > NAPLEX: Infectious Disease II (Bacterial) > Flashcards

NAPLEX: Infectious Disease II (Bacterial) Flashcards

1
Q

Pre-operative ABX- administer Cefazolin _______ minutes before sx and quinolone or vancomycin _______ minutes before sx

A

Cefazolin 60
Quinolone or Vanco 120

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2
Q

Preferred abx for cardiac, ortho, or vascular SSI prophylaxis if CI to cefazolin (allergy)

A

Clindamycin

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3
Q

Empiric abx for meningitis: Neonates

A

Ampicillin
+
Cefotaxime or gent

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4
Q

Empiric abx for meningitis: Age 1 to 50 not immunocomp

A

Ceftriaxone or Cefotaxime
+
Vanco

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5
Q

Empiric abx for meningitis: >50 or immunocomp

A

Ampicillin
+
Ceftriaxone or cefotaxime
+
Vanco

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5
Q

Most common pathogens causing AOM

A

M catt
Haemophilis
Strep pneumo

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6
Q

First line for AOM?

Allergy first line for AOM?

A

Augmentin or Amoxicilllin

2nd or 3rd gen cephalosporine

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7
Q

When to initiate antibiotics for AOM

A

<6 mo
6-23 mo and bilateral
Severe

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8
Q

Preferred abx for COPD exacerbation and duration

A

Augmentin
Azithro

5 days

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8
Q

When to initiate abx for acute sinusitis

A

> 10 days symptoms
3 days severe symptoms
Temp >102

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9
Q

Which abx to treat pertussis

A

macrolides (azithro)

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10
Q

A false + TST test can occur in those who recieved ________

A

BCG vaccine

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11
Q

Diagnosis of Latent TB- criteria for + skin test
What mm induration indicates TB

A

> 5 if immunocomp
10 if at risk (health care workers, from other countries)
15 no risk factors

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12
Q

Active TB treatment

A

RIPE x 2 months
RI x 4 mo

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13
Q

Latent TB treatment for Latent

A

Rifapentine + isoniazid x 3 months
Rifampin + Isoniazid x 3 months
Rifampin x 4 months
Isoniazid x 6-9 months

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14
Q

Which RIPE drugs causes incr LFTs

A

all of them

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15
Q

Which RIPE therapy causes hemolytic anemia

A

R, I

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16
Q

Which RIPE therapy causes DILE

A

pyrzinimide

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17
Q

Which RIPE therapy causes orange secretions

A

R

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18
Q

Which RIPE therapy causes peripheral neuropathy

A

I

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19
Q

Which RIPE therapy causes gout

A

P

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20
Q

Which RIPE therapy causes optic neuritis

A

E

21
Q

What is impetigo and how to treat it

A

honey colored crust by mouth
Mupirocin
or Cephalexin (if multiple)

22
Q

Nec Fasc abx

A

Vanco + Zosyn + Clinda (toxin production)

23
Q

3 regimens for uncomplicated UTI

A

Nitrofurantoin x 5 days (crcl>60)
Bactrim x 3 days (no sulfa ax)
fosfomycin x 1

24
Q

UTI and pregnancy first line regimen

A

Augmentin
Cephalexin
Ax: Fosfomycin

25
Q

Max days of Phenazopyradine

A

2

26
Q

Syphilis treatment (and allergy) Primary, secondary, or early latent

A

Pen G x 1
Doxy x 14 d

27
Q

Chlamydia treatment pregnancy and non

A

Pregnant: azithro x1
Non: doxy x 7d

28
Q

Syphilis treatment (and allergy) Late latent

A

Pen G weekly x 3 weeks
Doxy x 28 d

29
Q

Gonorrhea treatment

A

Ceftriaxone x 1 IM

30
Q

BV and Trich treatment

A

Metronidazole

31
Q

First line treatment for tickborne diseases (rocky mountain spotted fever, lyme disease)

A

Doxycycline

32
Q

What are the 4 antibiotic options for COPD exacerbations (if they require abx)

A
  1. Azithro
  2. Augmentin
  3. Resp fluoroquinolone
  4. Doxycycline
33
Q

Surgical site prophylaxis for GI surgery if patient has beta lactam allergy

A
  1. Clindamycin
  2. Metronidazole + Aminoglycoside
  3. Metronidazole + fluoroquinolone
34
Q

Surgical site prophylaxis abx for gastrointestinal surgery (4 options)

A
  1. Cefazolin + metronidazole
  2. Cefotetan
  3. Cefoxitan
  4. Unasyn
35
Q

Treatment options (2) for second recurrence of C diff

A
  1. Fidaxo 200 PO BID x 10 days
  2. Vancomycin pulse taper
36
Q

Treatment option for 3rd recurrence of c diff (2 options)

A
  1. Fecal transplant
  2. Vanco + Rifampin
36
Q

For a patient admitted for HAP with no risk for MRSA (nasal swab negative), what is first line treatment?

A

Beta lactam covering pseudomonas (Ceftaz, Cefepime, Zosyn)

DO NOT use Aztreonam, cipro, or aminoglycoside monotheraoy

37
Q

Outpatient options for CAP outpatient treatment

A
  1. Azithro + Augmentin
  2. Doxy
38
Q

Bacterial vaginosis or Trichomoniasis- which uses Metronidazole intravaginal cream and which uses PO?

A

BV- uses both
Trich- only PO

39
Q

Review Rifampin Drug interactions

A

Rifampin is a CYP3A4 inducer and P-glycoprotein inducer

39
Q

Community acquired intra abdominal infections treatment options

A
  1. Metronidazole + quinolone (if allergy)
  2. Metronidazole + Ceftriaxone
  3. Ertapenem
40
Q

Which are correct regarding AZO?
1. Seperate from dairy
2. Take with food to avoid upset stomach
3. Max 2 days
4. Urine red orange color
5. Helps symptoms but not infection

A

All but 1 are correct

41
Q

When do you use rectal vanco and IV metronidazole in c diff

A

Fulminant

42
Q

Match the organism to the gram negative stain:
Ecoli, N. Meningiditis, H flu
Cocci in pairs, Coccibacilli, Bacilli

A

Cocci: N Meningiditis
Coccibacilli: E coli
Bacilli: H flu

43
Q

What is the time cut off for diagnosising Primary/secondary/early latent versus Tertiary/late latent

A

above 1 year is tertiary/late latent

43
Q

When do you use a 3 drug regimen in VAP?

A

If a patient has been in the hospital and received abx within the last 90 days (risk for multidrug resistance

Meropenem + AG + Vanco

44
Q

If a patient has both chlamydia and gonorrhea, which ABX is best

A

Ceftriaxone x 1

45
Q

Pregnant patient with latent TB treatment

A

Rifampin + Isoniazid x 3 months
Rifampin x 4 months
Isoniazid x 6-9 months

(All the non-pregnant options EXCEPT INH+ Rifapentine)

45
Q

Endocarditis prophylaxis prior to dental surgery- Allergy

A

Normal is Amox 2g
Allergy= Doxycycline or Azithro

46
Q

State the result expected with each test in someone with latent TB:
a). Chest Xray
b). Acid Fast Bacili sputum smear
c). Interferon gamma release assay blood test
d). Intradermal tuberculin skin test

A
  • Chest Xray
  • Acid Fast Bacili sputum smear
    + Interferon gamma release assay blood test
    + Intradermal tuberculin skin test
47
Q

Which 2 drugs are continued in the continuation phase of TB treatment

A

R and I

Uworld NAPLEX (13 decks)

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