NAPLEX: Infectious Disease II (Bacterial) Flashcards
Pre-operative ABX- administer Cefazolin _______ minutes before sx and quinolone or vancomycin _______ minutes before sx
Cefazolin 60
Quinolone or Vanco 120
Preferred abx for cardiac, ortho, or vascular SSI prophylaxis if CI to cefazolin (allergy)
Clindamycin
Empiric abx for meningitis: Neonates
Ampicillin
+
Cefotaxime or gent
Empiric abx for meningitis: Age 1 to 50 not immunocomp
Ceftriaxone or Cefotaxime
+
Vanco
Empiric abx for meningitis: >50 or immunocomp
Ampicillin
+
Ceftriaxone or cefotaxime
+
Vanco
Most common pathogens causing AOM
M catt
Haemophilis
Strep pneumo
First line for AOM?
Allergy first line for AOM?
Augmentin or Amoxicilllin
2nd or 3rd gen cephalosporine
When to initiate antibiotics for AOM
<6 mo
6-23 mo and bilateral
Severe
Preferred abx for COPD exacerbation and duration
Augmentin
Azithro
5 days
When to initiate abx for acute sinusitis
> 10 days symptoms
3 days severe symptoms
Temp >102
Which abx to treat pertussis
macrolides (azithro)
A false + TST test can occur in those who recieved ________
BCG vaccine
Diagnosis of Latent TB- criteria for + skin test
What mm induration indicates TB
> 5 if immunocomp
10 if at risk (health care workers, from other countries)
15 no risk factors
Active TB treatment
RIPE x 2 months
RI x 4 mo
Latent TB treatment for Latent
Rifapentine + isoniazid x 3 months
Rifampin + Isoniazid x 3 months
Rifampin x 4 months
Isoniazid x 6-9 months
Which RIPE drugs causes incr LFTs
all of them
Which RIPE therapy causes hemolytic anemia
R, I
Which RIPE therapy causes DILE
pyrzinimide
Which RIPE therapy causes orange secretions
R
Which RIPE therapy causes peripheral neuropathy
I
Which RIPE therapy causes gout
P
Which RIPE therapy causes optic neuritis
E
What is impetigo and how to treat it
honey colored crust by mouth
Mupirocin
or Cephalexin (if multiple)
Nec Fasc abx
Vanco + Zosyn + Clinda (toxin production)
3 regimens for uncomplicated UTI
Nitrofurantoin x 5 days (crcl>60)
Bactrim x 3 days (no sulfa ax)
fosfomycin x 1
UTI and pregnancy first line regimen
Augmentin
Cephalexin
Ax: Fosfomycin
Max days of Phenazopyradine
2
Syphilis treatment (and allergy) Primary, secondary, or early latent
Pen G x 1
Doxy x 14 d
Chlamydia treatment pregnancy and non
Pregnant: azithro x1
Non: doxy x 7d
Syphilis treatment (and allergy) Late latent
Pen G weekly x 3 weeks
Doxy x 28 d
Gonorrhea treatment
Ceftriaxone x 1 IM
BV and Trich treatment
Metronidazole
First line treatment for tickborne diseases (rocky mountain spotted fever, lyme disease)
Doxycycline
What are the 4 antibiotic options for COPD exacerbations (if they require abx)
- Azithro
- Augmentin
- Resp fluoroquinolone
- Doxycycline
Surgical site prophylaxis for GI surgery if patient has beta lactam allergy
- Clindamycin
- Metronidazole + Aminoglycoside
- Metronidazole + fluoroquinolone
Surgical site prophylaxis abx for gastrointestinal surgery (4 options)
- Cefazolin + metronidazole
- Cefotetan
- Cefoxitan
- Unasyn
Treatment options (2) for second recurrence of C diff
- Fidaxo 200 PO BID x 10 days
- Vancomycin pulse taper
Treatment option for 3rd recurrence of c diff (2 options)
- Fecal transplant
- Vanco + Rifampin
For a patient admitted for HAP with no risk for MRSA (nasal swab negative), what is first line treatment?
Beta lactam covering pseudomonas (Ceftaz, Cefepime, Zosyn)
DO NOT use Aztreonam, cipro, or aminoglycoside monotheraoy
Outpatient options for CAP outpatient treatment
- Azithro + Augmentin
- Doxy
Bacterial vaginosis or Trichomoniasis- which uses Metronidazole intravaginal cream and which uses PO?
BV- uses both
Trich- only PO
Review Rifampin Drug interactions
Rifampin is a CYP3A4 inducer and P-glycoprotein inducer
Community acquired intra abdominal infections treatment options
- Metronidazole + quinolone (if allergy)
- Metronidazole + Ceftriaxone
- Ertapenem
Which are correct regarding AZO?
1. Seperate from dairy
2. Take with food to avoid upset stomach
3. Max 2 days
4. Urine red orange color
5. Helps symptoms but not infection
All but 1 are correct
When do you use rectal vanco and IV metronidazole in c diff
Fulminant
Match the organism to the gram negative stain:
Ecoli, N. Meningiditis, H flu
Cocci in pairs, Coccibacilli, Bacilli
Cocci: N Meningiditis
Coccibacilli: E coli
Bacilli: H flu
What is the time cut off for diagnosising Primary/secondary/early latent versus Tertiary/late latent
above 1 year is tertiary/late latent
When do you use a 3 drug regimen in VAP?
If a patient has been in the hospital and received abx within the last 90 days (risk for multidrug resistance
Meropenem + AG + Vanco
If a patient has both chlamydia and gonorrhea, which ABX is best
Ceftriaxone x 1
Pregnant patient with latent TB treatment
Rifampin + Isoniazid x 3 months
Rifampin x 4 months
Isoniazid x 6-9 months
(All the non-pregnant options EXCEPT INH+ Rifapentine)
Endocarditis prophylaxis prior to dental surgery- Allergy
Normal is Amox 2g
Allergy= Doxycycline or Azithro
State the result expected with each test in someone with latent TB:
a). Chest Xray
b). Acid Fast Bacili sputum smear
c). Interferon gamma release assay blood test
d). Intradermal tuberculin skin test
- Chest Xray
- Acid Fast Bacili sputum smear
+ Interferon gamma release assay blood test
+ Intradermal tuberculin skin test
Which 2 drugs are continued in the continuation phase of TB treatment
R and I
