Naphthalene and opioids Flashcards
Describe the MOT of Naphthalene
Poisoning from naphthalene destroys or changes red blood cells so they cannot carry oxygen.
Naphthalene may produce hemolysis, especially in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Describe the clinical presentation of napht
Acute ingestion usually causes prompt nausea, vomiting and diarhhea.
Volatile, and inhalation of vapors may cause eye, nose, and throat irritation.
Agitation, lethargy, and seizures may occur with naphthalene ingestion.
Chronic inhalation has also caused hemolytic anemia (abnormal breakdown of RBC).
describe Emergency and supportive measures
of napt
Maintain an open airway and assist ventilation if necessary.
Treat coma and seizures if they occur.
Treat hemolysis and resulting hemoglobinuria, if they occur, by intravenous hydration and urinary alkalinization.
Describe Decontamination
of napt
Administer activated charcoal orally if conditions are appropriate.
Gastric lavage is not necessary after small to moderate ingestions if activated charcoal can be given.
Inhalation
Remove the victim from exposure; fresh air is all that is required.
describe Enhanced elimination and antidotes of nap
none
Describe the MOT of opiods
Opioids stimulate several specific opiate receptors in the CNS, causing sedation and respiratory depression.
Death from respiratory failure
Receptors for opioids
: (Mu (μ),Delta (δ),Kappa (κ),opioid receptor like-1 (ORL1)