N410 Peds Fluids Flashcards
Releases Antidiuretic Hormone (ADH)?
Posterior pituitary gland
Hormone that promotes water retention in the renal system by increasing the permeability of renal tubules to water?
Antidiuretic Hormone (ADH)
Low ADH (too much water loss, hyperosmolarity) ex = DI High ADH (SIADH: hyponatremia and hypo-osmolality) ex = cancer, CF
Hormone secreted by the adrenal cortex?
Aldosterone
What does aldosterone do?
Hormone that enhances SODIUM REABSORPTION in renal tubules, thus promoting osmotic REABSORTPION OF WATER.
It’s release is stimulated by angiotensin (Renal renin-angiotensin stystem).
Why is ADH released?
In response to increased osmolality and decreased volume of intravascular fluid.
Diminished blood flow to the kidneys stimulates what?
Renin angiotensin system
What hormone does the renin-angiotensin system generate and what does it do?
ANGIOTENSIN: Vasoconstrictor and stimulates reabsorption of water in tubules
Hormone that enhances sodium reabsorption in renal tubules, thus promoting osmotic reabsorption of water. Renin secretion leads to generation of angiotensin, a powerful vasoconstrictor. Angiotensin also stimulates the release of aldosterone.
Type of water loss through skin and respiratory tract
Insensible water loss
High insensible water loss: Radiant warmers Phototherapy Skin defects and skin breakdown (burns) Fever The proportionately longer gastrointestinal tract in infancy (diarrheal losses) • Increased temperature • Increased humidity • Hyperventilation • Diabetes insipidus • Hyperglycemia
Decreased losby:
Humidified mechanical ventilation
hypothyroid
hypothermia
Conditions with decreased fluid requirements:
- Heart failure
- Syndrome of inappropriate antidiuretic hormone
- Mechanical ventilation
- After surgery
- Oliguric renal failure (decreased UO)
- Increased intracranial pressure
What leads to the increased risk of dehydration in the pediatric population?
More ECF to lose and lost quickly
Increased BSA body surface area (in relation to the mass of active tissue)
Increased BMR basal metabolic rate (higher to support cellular and tissue growth)
Increased insensible losses through fever
Immature kidneys
S/Sx of severe dehydration?
alert to comatose
fontanels sunken
deeply sunken eye orbits
oral mucosa dry
tenting
heart rate increased, progressing to bradycardia
blood pressure normal, progressing to hypotension
extremities cool, mottled or dusky
significantly delayed capillary refill
urine output significantly less than 1 ml//kg/hour
What is gastroenteritis?
Inflammation of the GI tract w/ vomiting, fever and diarrhea.
What is considered diarrhea?
> 3 water stools/day
DEHYDRATION: When water is lost and sodium concentration becomes elevated, kidneys react by:
Compensatory mechanisms in the kidney stop ADH secretion so water is retained.
Which of the following is defined as the forces that favor filtration from the capillary
Capillary hydrostatic pressure and interstitial oncotic pressure