N365 Poiod Analgesics and Hypnotics

Question 1

What is Schedule II

Answer 1

most addictive drugs that can be used therapeutically.

Question 2

What class is Morphine?

Answer 2

Narcotic

Question 3

What is the action of Morphine?

Answer 3

CENTRAL action on perception of pain. Primary site of action is the sensory cortex and alters attitudes by psychological, sedative, and hypnotic effects. Agonist that interacts with Mu and kappa receptor. binds to receptors and stimulates a response.

Question 4

What are the CNS effects of morphine?

Answer 4

Analgesia, drowsiness, positive or negative changes in mood, mental clouding. Miosis, depresses brain stem and therefore respiratory center, triggers the post-medulla chemoreceptor trigger zone causing N&V

Question 5

What are morphine’s affects on the cardiovascular system?

Answer 5

can dialate resistance vessels leading to postural hypotension. can provoke the release of histamine, dialate cerebral vessels causing an increase in ICP.

Question 6

What are morphine’s affects on the GI system

Answer 6

decrease in motility leading to constipation, delay in gastro emptying.

Question 7

What are morphine’s affects on smooth muscle of the bladder esp?

Answer 7

causes an increase in urinary urgency(Increase in tone) and an increase in urinary retention by increasing the tone of the sphincter.

Question 8

What are morphine’s affect on the uterus and bronchials

Answer 8

Can prolong labor, decrease libido in males, and in large doses cause broncho constriction.

Question 9

What are morphine’s affects on the skin?

Answer 9

causes cutaneous blood vessels to dilate leading to a flushed warm face and neck and puritis. .

Question 10

What are the ADR’s for morphine?

Answer 10

High potential for abuse and tolerance, respiratory depression, constipation, urinary retention and urgency , can have allergic reaction, puritis.

Question 11

What class is merperidine demerol?

Answer 11

schedule II narcotic

Question 12

Why use merperidine (Demerol)?

Answer 12

Lower GI effects, less urinary retention, good for post anesthesia shivering.

Question 13

Why can’t demerol be used as often as morphine?

Answer 13

it’s protein bound and can build up in system, it’s only used short term.

Question 14

What is Percocet?

Answer 14

Oxycodone and acetaminophenm Schedule II

Question 15

What is Percodan?

Answer 15

Oxycodone and aspirin

Question 16

What is Vicodin and Norco

Answer 16

hydrocodone and acetaminophen (schedule II or III).

Question 17

What is Dilaudid?

Answer 17

hydromorphone, potent not powerful.

Question 18

What is Naloxone (Narcan)

Answer 18

Narcotic antagonist

Question 19

What is the action of naloxone (Narcan)?

Answer 19

Pure antagonist, block opiod receptors.

Question 20

What are the ADR’s for Narcan?

Answer 20

Will cause withdrawal symptoms, pain returns immediately.

Question 21

Special information about Narcan (Naloxone).

Answer 21

Used to revice narcotics effects of anesthesia or overdose. Naltrexone (Revia) is used for alcohol dependence/withdrawal.

Question 22

What classification is Nalbuphine (Nubain)?

Answer 22

Narcotic agonist antagonist (Stimulates one receptor and blocks another).

Question 23

What is the action of Nalbuphine (Nubaine)

Answer 23

combines with kappa receptors producing analgesia, and acts as a partial antagonist at Mu receptors. Provides short intermittent pain relief.

Question 24

What are the ADR’s of Nalbuphine (Nubaine)?

Answer 24

Sedation, sweatiness, clamminess, N&V, dizzyness, vertigo, dry mouth, headache, respiratory depression.

Question 25

Special information about Nalbuphine (Nubaine).

Answer 25

is reversed by narcan

low abuse potential

Question 26

What classification is codeine?

Answer 26

Narcotic analgesic, and antitussive (cough suppressant).

Question 27

What is the action of morphine?

Answer 27

binds to opiod receptors to produce mild to moderate pain relief. 30mg morphine = 325 mg of aspirin or acetaminophen.

Question 28

What are the ADR’s for codine?

Answer 28

respiratory depression, constipation, urinary retention, miosis.

Question 29

Special information for codine

Answer 29

higher dosage needed for pain release.
very effective cough suppressant at 10mg
200mg codeine = 30 mg morphine

Question 30

What is Zolpidem (ambien)

Answer 30

Hypnotic, non BZD

Question 31

What is the action of Zolpidem (Ambien)?

Answer 31

binds to benzodiazepine receptors in brain.

Question 32

What are the SDR’s for Zolpidem (Ambien)?

Answer 32

dizziness, headache, nausea, diarrhea, next day drowsiness, sleep driving and sleep behaviors.

Question 33

What are the new dosages for Zolpidem (Ambien)?

Answer 33

5mg for women, 10mg for men (CUT IN HALF).

Question 34

What is Ambied CR

Answer 34

extended release ambien

Question 35

What is Ambien scheduled as?

Answer 35

IV

Question 36

What is ambien like?

Answer 36

it is an hypnotic that acts like a benzodiazepine.

Question 37

Special information Ambien

Answer 37

Short term treatment no associated with any withdrawal symptoms, tolerance, or dependence.