N-Oxide reduction Flashcards
1
Q
What is this reaction similar (but opposite) to?
A
This reaction is similar to N-oxidation but is the opposite
2
Q
What happens in this reaction?
A
The N-O group is reduced, so lost of Oxygen, and gain of an electron lone pair.
3
Q
Where does this reaction occur and what are the conditions required?
A
Gut microflora, andaerobic conditions
4
Q
Why would a drug be administered as N-oxide?
A
It has a faster onset of action, and fewer side effects