myometrial stimulants and relaxants

Question 1

name the myometrial stimulant drugs?

Answer 1

1. Prostaglandins
2. Oxytocin
3. Carbetocin
4. Ergometrine
5. Methylergometrine

Question 2

name the prostaglandins included in myometrial stimulation?

Answer 2

Etiproston

Luprositol

Dinoprost

Question 3

name the uses of oxytocin?

Answer 3

1. during dystocia
2. increase milk let down (mastitis)
3. helps stop uterine bleeding (useful after parturition or after caesarian)
4. reposition of uterine prolapse
5. help with retention of foetal membrane and eggs

Question 4

list the side effects associated with oxytocin?

Answer 4

1. GI
2. CV-system
3. swelling at inj. site

Question 5

name the veterinary oxytocin drugs available?

Answer 5

oxytocin inj.

oxytocina inj.

oxytocine inj.

Dila-part inj.

Perilacton nasal spray

Question 6

What is Carbetoin?

Answer 6

synthetic anologue of oxytocin

much longer half life (once daily inj.)

Question 7

describe Ergometrine?

Answer 7

potent uterine stimulant

Rarely used during parturition

Post-partum (haemorhage, retained placenta) promotes the expulsion of the contents of the uterus

Question 8

describe the use of Methylergometrine?

Answer 8

same as ergometrine but without the vasoconstrictive activity

Question 9

name the Myometrial relaxants?

Answer 9

B2-adrenoceptor agonists

Antispasmodics

Question 10

Name the B2 - adrenoceptor agonists used as myometrial relaxants?

Answer 10

Clenbuterol

Terbutaline

Question 11

name the anti-spasmodics used as myometrial relaxants?

Answer 11

Papaverine

Drotaverine

Denaverine

Question 12

list the indications for the use of myometrial relaxants?

Answer 12

1. inhibition of premature labour
2. difficult labour - when malpresentation correction is required
3. intrauterine foetal procedure
4. Reposition of uterus
5. procurement of embryos from donors, and implantation into recipients

Question 13

describe the action of myometrial relaxants?

Answer 13

inhibit the action of oxytocin

Question 14

name the anticholinergic substance that can be used as a myometrial relaxant?

Answer 14

Atropine

Question 15

Name the side effects of prostaglandins?

Answer 15

colic like disorders

Nausea

Vomiting

diarrhoea

bronchoconstriction