Myo Ischemia and Infarct Intro Flashcards

1
Q

Myo O2 supply:

O2 delevered thru?

Returned thru?

A

Coronary arteries deliver O2 blood to myo cells

Coronary veins return deO2 blood to RA via coronary sinus

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2
Q

Myo Ischemia is?

A

Inadequate blood supply of O2
Reversible
No permanent damage

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3
Q

Ischemia affects what region first?

Why?

A

sub-endo

farthest from supply and has greatest wall tension

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4
Q

Ischemia caused by?

A
Atherosclerosis
Vasospasm
Thrombosis/embolism
↓ vent fill time (tachy)
↓ coronary artery fill pressure (hypoTN, aortic valave dz)
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5
Q

Myo Infarct is?

A

death of myo cells

replaced w/ scar tissue

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6
Q

Breakdown products of cell death are? (3)

A

troponin
CK-MB
myoglobin

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7
Q

Myo injury is?

A

cell damage beyond ishemia

w/o tissue necrosis

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8
Q

Ischemia appears as what on ECG?

A

Inverted T waves (delayed repol)

Tall/peaked T waves

Depressed ST seg

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9
Q

Transmural Ischemia is?

A

ischemia of full myo wall,
repol takes longer,
repol can reverse from endo to epi

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10
Q

Transmural Ischemia appears as what on ECG?

A

Symmetrical/inverted T waves, V2-4

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11
Q

Peaked T waves (hyperacute) defined as?

A

> 6mm tall in limb leads
12mm tall in precord leads
OR
2/3 height of R wave

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12
Q

ST segment depression significant when?

A

> 1mm below baseline w/i 0.04 sec of J point

In more than one lead

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13
Q

Subendo Ischemia/Injury/Infarct is?

A

involvment of inner heart w/o extending thru whole vent wall

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14
Q

Subendo Infarct/Injury appears as what on ECG?

A

Flat ST seg w/ slight T inversion

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15
Q

ST segment elevation significant when?

A

> 1mm above baseline, 0.04 sec to R of J point

In more than one lead looking at same part of heart

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16
Q

Pathological Q waves are?

A

> 0.04 sec,
1/3 height of R in same complex,
More than one contiguous leads

Result of dead tissue (electrically silent)

17
Q

Injury appears as what on ECG?

A

ST elevation in leads facing injury (incomplete depol)

18
Q

Infarct appears as what on ECG?

A

pathologic P waves (electrically silent tissue)

19
Q

Right Coronary Artery perfuses?

A

RA, RV

Inf/Post walls of LV

20
Q

Left Main Coronary Artery divides into?

A

L Ant Descending branch

Left Circumflex branch

21
Q

Left Ant Descending branch perfuses?

A

Ant/Lat LV
Ant 2/3 vent septum
R & L BB

22
Q

Left Circumflex branch perfuses?

A

LA

Lat and Post LV