Myeloid

Question 1

From what stage is MPO expressed

Answer 1

Promyelocyte

Question 2

NK cell

Answer 2

Cd 3- cd16 cd 56

Question 3

11b, macrophage

Answer 3

11b, 68 , 163

Question 4

Monocyte

Answer 4

15, 16, 64

Question 5

Neutrophils

Answer 5

15, 16, 49d(-)

Question 6

Antigens of I maturity

Answer 6

Cd 34, 117 38

Question 7

Aberrant myeloid antigen expression

Answer 7

Can be seen in some cases of b all

Rare in T all unless early precursor t all

Question 8

Cd 56

Answer 8

It is most frequently seen in CMML (80% or so of cases ) and acute monoblastic/ monocytic leukaemias (up to 50% of cases). It is also found in other AML subtypes as well as in cases of MDS, T ALL, mature T- and NK-cell neoplasms, myeloma and blastic plasmacytoid dendritic cell neoplasm.

Question 9

Apml flow

Answer 9

CD117 +, CD64 +, CD33 +, CD13 + and MPO + but HLA-DR and CD34

Question 10

Splenic mzl

Answer 10

monoclonal (kappa restricted) B-cell lymphoid population was identified which showed strong CD20 expression together with FMC7, HLA-DR, CD79b and CD22. These cells were negative for CD5, CD10 and CD23
Sttong cd 20 makes it an excelkeng target for ritux