Mycology Flashcards

1
Q

what are the two categories of fungal agents?

A

fungal pathogens and opportunistic fungi

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2
Q

What factors increase the risk of opportunistic mycoses?

A

invasive medical procedures and medical therapies

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3
Q

what is the most common type of mycosis?

A

fungal infections

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4
Q

what are the three categories of clinical manifestation of fungal diseases?

A

fungal infections
toxicoses
allergies

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5
Q

what causes toxicoses?

A

acquired through ingestion
(when poisonous mushrooms are eaten)

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6
Q

What is used to culture and grow fungi?

A

sabouraud dextrose agar

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7
Q

Why do fungi often resist T cell-mediated immune responses?

A

fungi are biochemically similar to human cells and can harm human cells

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8
Q

what is the gold standard of antifungals?

A

amphotericin B

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9
Q

what is the two-step treatment for opportunistic infection?

A

high dose: treatment to reduce pathogens
low dose: maintenance therapy

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10
Q

How is Nystatin used in anti fungal therapies?

A

topically

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11
Q

What do -azole drugs target in fungal cells?

A

target ergosterol (biosynthetic enzyme)

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12
Q

What are some fungi against which scientists have developed vaccines?

A

Candida
coccidiosis
blastomycosis

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13
Q

What four pathogenic fungi cause systemic infections?

A

Blastomyces
Coccidioides
Histoplasma
Paracoccidioides

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14
Q

What is the division of these fungi Blastomyces
Coccidioides, Histoplasma, Paracoccidioides?

A

ascomycota

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15
Q

How are ascomycota infections aquired?

A

inhalation of spores
starts as pulmonary infection > to blood

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16
Q

What is unquie about ascomycota fungi?

A

dimorphic
have different manifestation in environment and in host

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17
Q

what is the most fungal infection affecting humans?

A

Histoplasmosis

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18
Q

Where is Histoplasmosis found?

A

in soils containing high nitrogen levels

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19
Q

what are the clinical manifestations of Histoplasmosis?

A

chronic pulmonary
ocular
chronic cutaneous
systemic

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20
Q

What is the causative agent of Histoplasmosis?

A

Histoplasma capsulatum

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21
Q

What is the causative agent of Blastomycosis?

A

Blastomyces dermatitidis

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22
Q

Where is Blastomycosis found?

A

in soils rich in organic matter

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23
Q

what is the most common manifestation of Blastomycosis?

A

pulmonary Blastomycosis

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24
Q

What pathogenic fungi is also known as “valley fever”?

A

Coccidioidomycosis

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25
What is the causative agent of Coccidioidomycosis?
Coccidioides immitis
26
Where is Coccidioidomycosis found?
desert soil rodent burrows
27
what conditions does Coccidioidomycosis result in?
pulmonary
28
What is the causative agent of Paracoccidioidomycosis?
Paracoccidioides brasiliensis
29
What pathogenic fungal disease is most common in farm workers?
Paracoccidioidomycosis
30
how does Paracoccidioidomycosis manifest in the body?
as a pulmonary condition causes chronic inflammatory disease of mucous membranes
31
what is the morpholgy of Paracoccidioides brasiliensis?
steering wheel
32
Opportunistic infections typically affect whom?
those with poor immunity AIDS pt
33
What are the 5 opportunistic fungi?
Pneumocystis Candida Aspergillus Cryptococcus Mucor
34
what is the causative agent of Pneumocystis?
Pneumocystis jiroveci
35
This opportunistic fungi is an opportunistic fungal infection of AIDS patients?
Pneumocystis
36
What is the causative agent of Candidiasis?
Candida albicans
37
these opportunistic fungi are common members of the microbiota of skin and mucous membranes
Candidiasis
38
What are some clinical manifestations of Candidiasis?
thrush vaginal yeast infection nail infestions
39
What is the causative agent of Aspergillosis
Aspergillosis
40
This opportunistic fungi is caused by the the inhalation of fungal spores?
Aspergillosis
41
This opportunistic fungi only causes allergies.
Aspergillosis
42
where does Aspergillosis manifest?
lungs eye ears sinuses
43
what is the causative agent of Cryptococcosis?
Cryptococcus neoformans
44
This opportunistic infection results from inhalation of spores or dried yeast in bird dropping
Cryptococcosis
45
what are the clinical manifestations of Cryptococcosis?
pulmonary pneumonia meningitis
46
This type of mycoses is the most common type of fungal infections
superficial mycoses
47
Black and white piedra are what kind of mycoses?
superfical
48
This superficial infection is characterized by nodules on the shaft and transmitted through bushes or combs
Black and white piedra
49
Dermatophytoses are what kind of mycoses?
superfical
50
This superficial mycoses is a fungal infection of the skin or nails and was called ringworms.
Dermatophytosis
51
Malassezia infections are what type of mycoses?
superfical
52
This superficial mycoses causes pityriasis on the skin
Malassezia
53
what type of mycoses is Sporotrichosis?
Cutaneous and Subcutaneous Mycoses
54
what is the causative agent of Sporotrichosis
Sporothrix schenckii
55
This subcutaneous infection is limited to arms and legs?
Sporotrichosis
56
This toxin is produced by fungi during metabolic activities and consumed in grains and vegetables
mycotoxins
57
This toxin is the most well-known mycotoxins and is fatal to many vertebrates and used to make drugs.
aflatoxins
58
This fungal intoxication is caused by mushroom poisoning
Mycetismus
59
What is the deadliest mushroom toxin called?
death cap
60
Fungal allergens cause what time of reaction?
type I hypersensitivity (asthma, hay fever eczema)