Mycobacterium Flashcards
1
Q
Virulence factor of M. Tuberculosis. Gove MOA
A
Sulfatide - prevents lysosome and phagosome fusion
Cord factor - inhibits chemotaxis
2
Q
Indication of primary tuberculosis infection
A
Ghon complex
3
Q
Indication of secondary tuberculosis infection
A
Apex
4
Q
Extrulmonary TB at the vertebrate
A
Pott’s disease
5
Q
Gold standard for dx of TB
A
Sputum microscopy
6
Q
Culture media for M. Tuberculosis
A
Lowenstein Jensen medium
7
Q
Inhibits mycolic acid synthesis
A
Isoniazid
8
Q
Inhibits DNA dependent RNA polymerase
A
Rifampicin
9
Q
Inhibits arabinogalactan synthesis
A
Ethambutol
10
Q
2nd line anti-TB
A
Streptomycin Polypeptides Fluoroquinolones Thioamides Cycloserine P-aminosalicylic acid
11
Q
Causes TB in AIDS patient
A
M. Aviun intracellulare
12
Q
Yellow bacillus
A
M. Kansaii
13
Q
Hansen’s bacillus
A
M. Leprae
14
Q
Koch’s bacillus
A
Mycobacterium tuberculosis
