Mycobacteria

Question 1

What are the two types of leprosy?

Answer 1

Question 2

Answer 2

erythema nodosum leprosum, complement activation following immune complex deposition from leprosy

Question 3

gram+, acid fast, non-branching bacillus in blood culture at 72 hours in a septic patient with a line

Answer 3

myobacterium mucogenicum

rapid-growing Mycobacterium - associated with CLABSI sepsis

Question 4

What are two heme-related issues with dapsone?

Answer 4

hemolysis in G6PD patient
-elevated LDH, normal pulse ox, etc
-stop dapsone, transfuse if necessary

AND

methemoglobinemia
-low pulse-ox compared to Po2
-stop dapsone, give methylene blue

Question 5

abscessus

Answer 5

rapid grower
ERM gene (macrolide resistance)

Question 6