my revision: wk 3 associated medicines with glucocorticosteroid therapy

Question 1

cyclosporine

Answer 1

an immunosuppressant used for atopic dermatitis and immune mediated skin disorders

oral solution or ointment

SE: vomiting, gingival hyperplasia (overgrowth of gum) and hair overgrowth

Question 2

lokivetmab

Answer 2

treat atopic dermatitis in dogs

DOA is 4-8 weeks

administered through SC injection

MOA - blocks the action of interleukin 31 which causes itchiness

Question 3

azathioprine

Answer 3

cytotoxic (kills cells/used for cancer) but can be used with the glucocorticosteroids prednisoline & prednisone

DO NOT USE IN CATS

effects the S phase of the cell cycle

available in tablet form or as an injection

SE: bone marrow suppression, diarrhoea

Question 4

cyclophosphamide

Answer 4

cytotoxic drug

available as injection

SE (can be rlly bad): bone marrow suppression, haemorrhagic cystitis (bladder), diarrhoea

Question 5

chlorambucil

Answer 5

cytotoxic drug

SE: bone marrow suppression & anorexia