My Clinical Trials Flashcards

1
Q

RSP is the same as —-

A

CTLC

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2
Q

BMBX means:

A

bone marrow biopsy

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3
Q

CNF stands for:

A

case notification form (for Tissue Core notification samples)

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4
Q

MCC 18926 disease:

A

MDS (Myelodysplastic Syndromes)

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5
Q

MCC 19429 disease:

A

Myelofibrosis

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6
Q

MCC 20331 disease:

A

MPN (Myeloproliferative Neoplasms)

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7
Q

MCC 19737 study drug:

A

ruxolitinib

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8
Q

Who is the PI for 18926?

A

Dr. Komrokji

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9
Q

Who is the PI for 19737?

A

Dr. Onyee Chan

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10
Q

Who is the PI for 20331?

A

Dr. Andrew Kuykendall

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11
Q

My phone extension

A

745-7943

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12
Q

For 18926, when do we collect Hair Follicles & Buccal Swabs?

A

Baseline and then optionally collected at M12 & M24.

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13
Q

MCC 20331 status?

A

Suspended

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14
Q

Name the 4 “closeout” studies from Caroline

A

19379, 20634, 19872, and 20061

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15
Q

MCC 20634 status and patients?

A

Closed to Accrual, all pt’s off study. “Early termination of trial by sponsor”

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16
Q

MCC 20061 status and patients?

A

Closed to Accrual, 3 patients on follow-up

17
Q

MCC 19379 status and patients?

A

Closed to Accrual, all pt’s off study

18
Q

MCC 19872 status and patients?

A

Closed to Accrual, 1 patient on follow up

19
Q

MCC 19872 study drug?

A

Luspatercept

20
Q

MCC 20061 study drug?

A

Vyxeos

21
Q

MCC 19429 P.I.?

A

Dr. Komrokji

22
Q

MCC 19872 sponsor and P.I.?

A

Acceleron and Celgene. Dr. Komrokji

23
Q

Which study used drug to prepare pt for transplant (induction)?

A

MCC 20061

24
Q

Which study evaluates which drug is most useful in reducing need for RBC transfusions?

A

MCC 19872

25
Q

“MMB vs. DAN in Symptomatic, Anemic Subjects w/ PMF, Myelofibrosis, or Post ET Myelofibrosis”

A

MCC 20634

26
Q

“A Pilot Study of Vyxeos for Transplant Eligible, Higher Risk Pt’s w/ Myelodysplastic Syndrome”

A

MCC 20061

27
Q

“Luspatercept vs Epoetin Alfa for the Treatment of Anemia due to IPSS-R”

A

MCC 19872

28
Q

CTLC is the same as —-

A

RSP

29
Q

Name the 2 Caroline studies that have no follow up patients

A

19379 and 20634

30
Q

Name the 2 Caroline studies that have follow up patients

A

19872 and 20061

31
Q

“Navitoclax Alone or in Combination w/ Ruxolitinib in Subjects w/ Myelofibrosis”

A

MCC 19429

32
Q

MCC 19429 sponsor and study drug?

A

AbbVie and Navitoclax

33
Q

MCC 20061 sponsor and P.I.?

A

Jazz Pharmaceuticals and Dr. Sallman

34
Q

MCC 19737 disease:

A

CML (Chronic Myeloid Leukemia)

35
Q

MCC 19429 status and patients?

A

Closed to Accrual, 1 patient ON FOLLOW UP (final cert was in August?)

36
Q
A