Mx - Rhesus Isoimmunisation Flashcards
1
Q
Approx 15% of mothers are Rhesus-negative, which, if sensitisation occurs, places future pregancies at risk of
A
haemolytic disease of the newborn (HDN) - which can result in fetal anemia with complications of hepatosplenomegaly (extramedullary erythropoeisis), cardiac failure, hydrops fetalis and fetal death.
2
Q
When should anti-D be given in the 1st trimester? What quantity?
A
250 IU, for CVS Miscarriage Termination Ectopic
3
Q
When should anti-D be given in the 2nd and 3rd trimesters? What quantity?
A
625 IU, for Obstetric haemorrage Amniocentesis ECV Abdo trauma PLUS - ALL Rh-negative women at 28 and 34 weeks PLUS - Post-natally within 72 hours
4
Q
The administration of Anti-D at 28 and 34 weeks results in reduction of alloimmunisation from
A
1% to 0.3%
