Mutuations Flashcards
What is a mutation?
Any change to the quantity or the base sequence of DNA
How do mutations affect transcription?
Triplet codes are transcripts into mRNA
Change in DNA sequence changes mRNA sequence
How do mutations affect translation?
Change in mRNA sequence changes amino acid order
Change in amino acids, changes the protein produced
If there is an increase in mutation what happens to variation?
Increase in mutations = increased variation
What are the 3 types of mutation?
Deletion, insertion, substitution
What is insertion?
A nucleotide is added to the DNA sequence
What is deletion?
A nucleotide is lost from the DNA sequence
What is substitution?
One nucleotide is replaced by another nucleotide with a different base
How many amino acids will be affected by substitution?
One
How many amino acids will be affected by deletion and insertion?
The whole amino acid sequence
What is frameshift
Every amino acid after the insertion or deletion will change
What are Chromosomal mutations
Changes in the structure or number of whole chromosomes
What are the two types of chromosomal mutations?
Changes in whole sets of chromosomes
Changes in number of individual chromosomes per cell