Mutations Occur Spontaneously + Randomly Flashcards
1
Q
how do spontaneous mutations occur
A
naturally
2
Q
when do spontaneous mutations often occur
A
during enzymatic DNA replication
3
Q
what is mutation rate
A
likelihood a gene will undergo a mutation in single gene expression
4
Q
what are DNA sequences highly susceptible to mutation called
A
mutation hot spots
5
Q
what causes induced mutations e.g
A
influence of exogenous factors (natural/artificial agents) e.g UV rays from sun
6
Q
how do you estimate mutation rate across entire genome
A
with rapid + economical whole-genome sequencing
7
Q
what cell mutation rates are higher
A
somatic
8
Q
what are somatic mutations responsible for
A
most cancer developments
other diseases
can cause new germ-line mutations
