Mutation Flashcards

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1
Q

refers to any change in the genetic material of the organisms.

A

Mutation

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2
Q

Occurs in any body cell except egg cell

A

Somatic Mutation

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3
Q

Occurs in the reproductive cell

A

Germ Mutation

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4
Q

Classification of Mutation

A

Mutation due to changes in chromosome number
Mutation due to change in chromosome structure
Gene mutation

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5
Q

Aberrations may include

A

Whole genome
Entire single chromosome
Parts of the Chromosomes

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6
Q

a change in the entire set of the Chromosomes

A

Euploidy

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7
Q

loss or addition of a single whole chromosome

A

Aneuploidy

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8
Q

Characteristics more common in plants than in animals

A

Polyploidy

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9
Q

Characterized by the multiplication of a single whole genome or chromosome

A

Autopolyploids

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10
Q

Types of structural changes in the Chromosome

A
  1. Deficiencies or Deletions
  2. Duplication or Repeats
  3. Inversion
  4. Interchange or Reciprocal
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11
Q

represent a loss of segment of the Chromosomes

A

Deficiencies or Deletions

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12
Q

When the section of the Chromosomes is in excess of the normal amount

A

Duplication or Repeats

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13
Q

due to the rotation of chromosome segment

A

Inversion

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14
Q

Occurs when the single break in two non homologous chromosomes

A

Interchange or Reciprocal Translocation

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15
Q

Involves a change in the nucleotide

A

Gene Mutation

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16
Q

Categories of Gene Mutation

A

Base pair substitution
Frameshift mutation

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17
Q

due to copy errors during DNA replication

A

Base pair substitution

18
Q

It is due to the substitution of purine with another purine or the substitution of one pyrimidine with another pyrimidine

A

Transition mutation

19
Q

Substitution of purine whith pyrimidine

A

Transversion Mutation

20
Q

an insertion or Deletion of a base that changes the reading frame of the entire subsequent sequence

A

Frameshift Mutation

21
Q

Classification of Gene Mutation

A

Base pair mutation
Frameshift Mutation

22
Q

Inversion which occurs when the centromere is not included in the inverted segment

A

Paracentric

23
Q

Inversion which occurs when the inverted segment includes the centromere

A

Pericentric

24
Q

Characterized by the multiplication of two or more genomes or chromosome sets

A

Allopolyploids

25
Q

Mutagenic Agents

A

Physical Mutagen
Chemical Mutagen
Environmental Mutagen

26
Q

Physical mutagen that can break the DNA strand

A

Ionizing Radiation

27
Q

Trisomy 21

A

Doen Syndrome

28
Q

Trisomy 18

A

Edward Syndrome

29
Q

Trisomy 13

A

Patau Syndrome

30
Q

2n=45, 22II

A

Turner’s Syndrome

31
Q

2n=47, 22II + XXY

A

Klinefelter’s Syndrome

32
Q

Mental retardation and premature menopause

A

Metafemale

33
Q

Antisocialism, aggressiveness, criminal tendency, and low IQ

A

Double Y Syndrome

34
Q

results to the formation of a termination or non sense codon

A

Non-Sense

35
Q

Results to substitution of an amino acid in the polypeptide chain

A

Missense

36
Q

does not change the type of amino acid in the polypeptide chain

A

Samesense

37
Q

Can impart enough energy causing mutation

A

Non ionizing radiation

38
Q

Changes CG pair to TA pair

A

Nitrous acid

39
Q

Substitute for DNA bases

A

Base analogues

40
Q

Inhibits spindle formation and prevents anaphase

A

Proflavin

41
Q

Blocks mitotic cells in metaphase

A

Colchicines