MUST KNOW HIGH YIELD!!!!! Flashcards
What is the triad seen in Toxoplasma lymphadenitis?
- Follicular hyperplasia
- Intrafollicular epithelioid histiocytes
- Monocytoid B-cells in sinuses (see pic)
PCR confirms
What testicular tumor has the best 10 year survival?
Spermatocytic seminoma
Which type of assay involves probe amplification?
I know super vague but just look at answer and know this
Invader assay
Name this salivary gland lesion.
Canalicular adenoma
Appendix or colon with this organism
Schistosomiasis
How do you monitor therapy following anticoagulation with lepirudin?
Lepirudin is a direct thrombin inhibitor that is used to treat pts with HIT
Due to its inhibitory effect on thrombin, lepirudin results in prolongation of both aPTT and prothrombin time (PT). The aPTT is generally the current method of choice for monitoring treatment with lepirudin in most situations.
What is shown in this esophageal brushing cytology specimen?
Reactive changes/repair
Esophageal squamous mucosa with reactive changes, consisting of uniform cells with nucleomegaly in a predominantly cohesive flat sheet
Gross photo of echinococcal cyst vs HCC
Which is this?
Echinococcal cyst
This is HCC
FNA Salivary gland tumor
Well differentiated mucoepidermoid carcinoma
FNA of lung lesion
Carcinoid
What Taenia spp is this?
T solium (armed rostellum)
What is this?
Kaposi sarcoma
What is this?
Bullous pemphigoid
What is the cell membrane issue with stomatocytes?
defect in sodium/potassium permeability of the RBC membrane (confers protection against P vivax)
Tell the difference between T. solium and T. saginata.
T solium does more damage (neurocysticercosis) and it has the hooks
Prostate:
adenosis or basal cell hyperplasia?
Adenosis
Here is BCH
What is this this lesion associated with?
Oral hairy leukoplakia
Almost exclusively occurs in AIDs patients and is associated with EBV. It presents as white plaques at the lateral border of the tongue.
What diagnosis should be considered in a pt with stomatocytes and hemolytic anemia?
Rh Null
LACK Lw antigen!!
*they could phrase it like this on exam (instead of saying Rh null, say lack Lw antigen–this is actually a Rh LIKE antigen but Rh null pts lack this)
What is this?
*one of the branching chain conidia fungi–don’t know how likely to see on test but just in case…..
Scopulariopsis
Where are benign papillary mesotheliomas commonly found?
Peritoneum, pericardium, and tunica vaginalis
Gross photo of this colon lesion.
Villous adenoma
What placental lesion is shown here?
What is seen in the fetus with this?
Amnion nodosum
Staghorn plaques on membranes, a condition characterized by yellow nodules of compressed squames and hair on the surface and membranes, is associated with severe, long-standing oligohydramnios
renal abnormalities seen in fetus
What is this lesion in the brain?
Progressive multifocal leukoencephalopathy
What is this lesion of the lower jaw?
Ameloblastoma
What is being shown in this cell from the lung?
Type II pneumocyte showing SURFACTANT (lamellated bodies)
Septal panniculitis is associated with?
Erythema nodosum
What is this lung lesion?
Sclerosing hemangioma of the lung
This lesion in the lung is seen more commonly in women with an average age in the 40s and shows papillary like projections lined by epithelioid cells with a central proliferation of polygonal mesenchymal appearing cells. Both populations are TTF1 positive indicating type II pneumocyte origin for this tumor.
What are the 3 stop codons?
UAG
UAA
UGA
What is this organism in the brain?
![](https://s3.amazonaws.com/brainscape-prod/system/cm/255/677/934/q_image_thumb.jpg?1464386585)
Naegleria fowleri
*I realize this concept is getting beat to death but be able to recognoize!
Lesion in 32 yo woman with cervical and groin LAD with prominent follicular hyperplasia.
What is this?
SLE Lymphadenitis
Architectural preservation, but follicular hyperplasia with variable sized follicles, increased vascularity, interfollicular immunoblasts and plasma cells.
Often well circumscribed areas of paracortical necrosis with necrosis of small vessels.
Occasionally DNA deposition/hematoxylin bodies (hematoxyphilic material) in stroma, sinuses and blood vessel walls.
May have giant follicles, often disarray of follicular dendritic cell network, no/rare granulomas, no/rare neutrophils.
giant cell lesion in patient post renal transplant, present in two jaw sites and in rib
Brown Tumor
What is this?
Pemphigus vulgaris
don’t forget about Hailey-Hailey (benign familial pemphigus) but that will have a dilapidated brick wall appearance (seen here)
What is this pancreas lesion?
Serous cystadenoma
What disease causes spores with organisms inside and squamous hyperplasia?
Rhinosporidiosis caused by Rhinosoridium seeberi - India/Sri Lanka endemic
Huge sporangia with endospores DDX includes coccidiodomycosis but is SMALLER
What percentage of LSIL will progress to HSIL?
10%
Two thirds of patients with LSIL will regress
What is this pancreatic lesion?
IPMN
What is this?
Follicular lymphoma
What is this lesion in the brain?
Amoebic encephalitis
What is this lung lesion?
Lipoid pneumonia
Cytology of urine showing this
Ileal conduit
degenerated columnar cells
What is this?
showing pleural lesion with granulation tissue, fibrosis and inflammation
Organizing fibrinous pleuritis (benign pleural lesion)
Common lesion posterior mediastiunum in kid
Ganglioneuroma
What is this?
Cellular Schwannoma
Name this specialized type of BCC found in groin, breast and ears.
Fibroepithelioma of pinkus
It is a eccrine duct BCC
What is this thyroid lesion in a 10 year old kid?
Medullary thyroid carcinoma
What is the factor VIII activity in female carriers?
50%
This is a lymph node from woman with history of endometriosis. What is diagnosis?
Endosalpingiosis
What is this pancreas lesion?
Nesidioblastosis
What causes sclerosing mediastinitis?
Histoplasma!
What is this?
Spitz nevus
What is this?
Coccidioides
Which is least likely to get HCC – HepB, HepC, Etoh, Hemachromatosis or Wilson’s?
Wilson’s
In order of decreasing likelihood: Hep C, hemachrom, Hep B, Etoh, Wilsons.
What is this retreperitoneal mass?
Well Differentiated Liposarcoma
Alpha hemolytic colony on blood agar that is bile soluble?
S. pneumo!
Bile solubility distinguishes from other alpha hemolytic colonies
What is this pancreas tumor?
Acinar cell carcinoma
What is this?
Adenomyosis
Most common location of Zollinger Ellison syndrome?
Duodenum
Showed this lesion in the bladder –who gets it?
Inflammatory pseudotumor
KIDS
Apoptosis causes all of the following except
- Councilman bodies
- GVHD crypt changes
- Tingible body macrophages
- Mallory bodies
d. Mallory bodies
A councilman body, also known as Councilman hyaline body or apoptotic body, is an acidophilic (eosinophilic / pink-staining on H&E) globule of cells that represents a dying hepatocyte often surrounded by normal parenchyma.
What is the most common malignant paratesticular tumor in children?
Spindle cell variant of embryonal rhabdomyosarcoma
What is this lesion?
Conventional osteosarcoma
What is this soft tissue lesion?
Myxoid liposarcoma
Name this breast lesion.
Nipple adenoma
Gross and micro photo of this liver lesion.
FNH
What lesion is seen on this pap smear?
Follicular cervicitis
What is this lesion?
Morton’s neuroma
What is this ovary lesion?
Lipid (steroid) cell tumor
What cardiac tumor is being shown?
Rhabdomyoma
MOST COMMONLY IN LEFT VENTRICLE
Most common primary cardiac tumor of
infancy and childhood
May be sporadic, but >50% associated with TS
Eosinophilic, polygonal cells with large glycogen-rich cytoplasmic vacuoles with stranding “spider cells”
What is this lesion seen in the lung?
Lipoid pneumonia
Exogenous lipoid pneumonia. The microscopic appearance of exogenous lipoid pneumonia is dependent on the composition of the aspirated material. (A) Exogenous lipoid pneumonia with histiocytes containing predominantly fine microvesicles. (B) Exogenous lipoid pneumonia with larger vacuoles and associated fibrosis
Can you tell the difference between Enterobius vermicularis egg and Hymenolepsis egg?
Which is this?
Hymenolepsis
This is Enterobius
What is the lesion and what is it associated with?
Plexiform neurofibroma
NF1
This finding is from a pregnant woman. What is it?
Amniotic fluid embolism
What kind of placenta is this?
Circumvallate placenta
This is a circumvallate placenta in which the membranes double back for a short distance over the fetal surface when the chorionic plate is too small.
Immunophenotype of what other lymphoid process does lymphomatoid papulosis most resemble?
Anaplastic Large Cell Lymphoma (CD30+)
Lymphomatoid papulosis aka pseudolymphoma is a primary cutaneous CD30+ T cell lymphoproliferative disorder with wedge shaped dermal infiltrate of atypical lymphocytes and a background of polymorphic inflammatory cells
What is this diagnosis of a lymph node?
Langerhans histiocytosis
What is this liver lesion?
Autoimmune hepatitis
FNA from head and neck area, what is this?
Normal parotid
Name this lesion.
Proliferating trichilemmal cyst
What is this?
Myxoid Chondrosarcoma
Mediastinal mass– a thymoma or nodular sclerosing Hodgkin’s.
Which is this?
Thymoma!
NS Hodgkin’s will have Reed Sternberg cells and the classic lacunar cells (spaces around histiocytes seen here)