Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Muskuloskeletal and Pain > Flashcards

Muskuloskeletal and Pain Flashcards

1
Q

How long does it take to see the effect of Allopurinol?

A

2 to 3 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How long does it take to see the effect of Febuxostat?

A

2 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are Febuxostat, Allopurinol and Colchicine used to treat?

A

Gout

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Can probenecid and sulfinpyrazone be used for acute attacks of gout?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How are gout drugs metabolized and excreted?

A

Metabolized in the liver, excreted in urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Can anti-gout drugs be prescribed to patients with renal impairment?

A

Yes, but cautiously

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What pregnancy category are allopurinol, colchicine, and febuxostat?

A

Pregnancy category C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What pregnancy category is Probenecid?

A

Pregnancy category B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What pregnancy category is Sulfinpyrazone?

A

Pregnancy category D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which antigout drugs may cause hepatotoxicity?

A

Allopurinol and colchicine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which antigout drug can cause significant diarrhea?

A

Colchicine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which antigout drugs may cause problems to a patient with a sulfa allergy?

A

Probenecid and sulfinpyrazone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which antigout drug may cause a maculopapular skin rash, especially in renal patients?

A

Allopurinol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which antigout drug may cause a patient to develop weakness related to myopathy and neuropathy?

A

Colchicine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which antigout drug is associated with vitamin B12 malabsorption?

A

Colchicine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which antigout drug has few drug-drug interactions?

A

Colchicine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which antigout drugs have lots of drug-drug interactions?

A

Probenecid, allopurinol, and sulfinpyrazone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which antigout drug increases the plasma levels of most penicillins and cephalosporins?

A

Probenecid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Which antigout drug is the first choice for acute gout attacks?

A

Colchicine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Which antigout drug is the drug of choice for prevention or urinary calculi?

A

Allopurinol

21
Q

Which antigout drug does NOT require a renal dose adjustment?

A

Febuxostat

22
Q

Which antigout drug is used for patients with chronic gout and hyperuricemia?

A

Febuxostat

23
Q

What drugs are also given during the first six months of febuxostat therapy?

A

NSAIDs or colchicine

24
Q

When is probenecid therapy started?

A

After the acute gout attack has resolved

25
Q

Why would you wean a patient off of probenecid?

A

Either the patient has had no gout attacks for six months or the patient’s uric acid levels have begun to rise

26
Q

What is the last resort antigout drug when both probenecid and allopurinol are not tolerated?

A

Sulfinpyrazone

27
Q

What should be closely monitored in all antigout drugs?

A

Serum uric acid levels

28
Q

What should be periodically monitored in patients taking probenecid and sulfinpyrazone and why?

A

CBC for blood dyscrasias

29
Q

What is the pregnancy category for corticosteroids?

A

Pregnancy category C

30
Q

Why are corticosteroids contraindicated in people with active untreated infections?

A

The drug may mask the signs and symptoms of the infection

31
Q

What is the best time of day to take corticosteroids?

A

In the morning before 9 am

32
Q

Why should a patient get an eye exam before beginning long-term corticosteroid treatment?

A

To check for cataracts and glaucoma

33
Q

Which NSAID or NSAID-like medication does not cause GI upset?

A

Acetominophen

34
Q

What is the pregnancy category of most NSAIDs?

A

Pregnancy category B or C

35
Q

At what point in the pregnancy should all NSAIDs be avoided?

A

the last trimester

36
Q

What pregnancy category is acetaminophen?

A

Pregnancy category B

37
Q

Which NSAID or NSAID-like medication irreversibly inhibits platelet aggregation?

A

Aspirin and salicylates

38
Q

How soon before surgery should a patient stop taking aspirin?

A

1 week before

39
Q

What is the pregnancy category of aspirin?

A

Pregnancy category D

40
Q

What drug therapies are recommended for acute visceral pain?

A

corticosteroids and NSAIDs

41
Q

Which NSAID or NSAID-like drug is SAFE for infants, pregnant patients and most elderly patients?

A

Acetaminophen

42
Q

What type of drug interactions should the NP be aware of when prescribing Celebrex or any other COX 2 inhibitors?

A

It is metabolized in the CYP portion of the liver

43
Q

What is the pregnancy category for opioid analgesics?

A

Pregnancy category C

44
Q

What are the names of the three opioid antagonists?

A

Narcan, Revia, and Revex

45
Q

What is the usual treatment for non-neuropathic pain?

A

NSAIDs

46
Q

What is the usual treatment for neuropathic pain?

A

Anti-epileptics such as Carbamazepine, Gabapentin, and Pregabalin

47
Q

Which antidepressants are often used to treat pain?

A

Tricyclic antidepressants such as amitryptiline

48
Q

How long does it take for pain to diminish when the patient is being treated with tricyclic antidepressants?

A

Several weeks

Pharmacology (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions