Infectious Diseases Flashcards

0
Q

When it comes to antibiotics, what is something to be aware of when changing locations?

A

Different locales have different resistances

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1
Q

What is the biggest cause of antibiotic resistance?

A

Overuse of broad spectrum antibiotics

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2
Q

What does the pneumococcal vaccine do?

A

It lessens bacterial resistance to antibiotics

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3
Q

What do natural penicillins work against?

A

strep, some enterococcus, some staph

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4
Q

What type of bacteria do aminopenicillins work on?

A

Gram negative urinary and GI pathogens

Common gram negative respiratory pathogens

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5
Q

What is a good general rule when it comes to dosing antibiotics?

A

Almost all ATBs require renal dosing

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6
Q

What can be used to broaden the spectrum of penicillin ATBs?

A

beta-lactimase inhibitors such as:
Clavulanate
Sulbactam
Tazobactam

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7
Q

What is an ADR to penicillin that many patients think is an allergic reaction?

A

A maculopapular rash occur in up to 9% of patients taking penicillin class drugs

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8
Q

What is the first line drug for infection following bites (including human)?

A

Amoxicillin/clavulanate

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9
Q

What is the first line drug for AOM and sinusitis?

A

Amoxicillin

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10
Q

What is the name of the fifth generation cephalosporin and what is it used to treat?

A

Ceftaroline (Teflaro), and it treats MRSA

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11
Q

How are cephalosporins excreted?

A

In the urine

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12
Q

If a patient had a very severe allergic reaction to penicillin, what other class of antibiotic should the NP avoid?

A

Cephalosporins

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13
Q

What two things should the NP monitor in all patients who are taking antibiotics?

A

Renal function and diarrhea (looking for C. diff)

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14
Q

What are the age limits on fluroquinolones?

A

Not for use in people under 18

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15
Q

What is the black box warning on fluoroquinolones?

A

May cause tendonitis/tendon rupture

16
Q

What should the nurse be aware of in regards to onset when prescribing fluoroquinolones?

A

It may have a delayed onset, as long as 120 days

17
Q

What kind of bacteria do fluoroquinolones work on?

A

most gram-negative bacteria

18
Q

What is the major problem with prescribing fluoroquinolones?

A

MANY bugs are resistant, including TB

19
Q

Can fluoroquinolones be used on pregnant patients?

A

No

20
Q

What disease states should fluoroquinolones be used in?

A
complicated UTI
pyelonephritis infections
chronic prostatitis
pneumonia
chronic bronchitis exacerbation
21
Q

How should fluoroquinolones be taken for best absorption?

A

On an empty stomach with a full glass of water

22
Q

What is an example of a lincosamide?

A

Clindamycin (Cleocin)

23
Q

What viruses is Acyclovir used on?

A
HSV 1 and 2
Varicella-zoster virus
Epstein-Barr virus
CMV
herpes virus 6
24
Q

What viruses is Valacyclovir used on?

A

The same viruses as acyclovir, since it converts in acyclovir after oral administration

25
Q

What viruses is Famciclovir used on?

A

HSV 1 and 2
Varicella-zoster virus
Epstein-Barr virus
hepatitis B virus