Infectious Diseases Flashcards
When it comes to antibiotics, what is something to be aware of when changing locations?
Different locales have different resistances
What is the biggest cause of antibiotic resistance?
Overuse of broad spectrum antibiotics
What does the pneumococcal vaccine do?
It lessens bacterial resistance to antibiotics
What do natural penicillins work against?
strep, some enterococcus, some staph
What type of bacteria do aminopenicillins work on?
Gram negative urinary and GI pathogens
Common gram negative respiratory pathogens
What is a good general rule when it comes to dosing antibiotics?
Almost all ATBs require renal dosing
What can be used to broaden the spectrum of penicillin ATBs?
beta-lactimase inhibitors such as:
Clavulanate
Sulbactam
Tazobactam
What is an ADR to penicillin that many patients think is an allergic reaction?
A maculopapular rash occur in up to 9% of patients taking penicillin class drugs
What is the first line drug for infection following bites (including human)?
Amoxicillin/clavulanate
What is the first line drug for AOM and sinusitis?
Amoxicillin
What is the name of the fifth generation cephalosporin and what is it used to treat?
Ceftaroline (Teflaro), and it treats MRSA
How are cephalosporins excreted?
In the urine
If a patient had a very severe allergic reaction to penicillin, what other class of antibiotic should the NP avoid?
Cephalosporins
What two things should the NP monitor in all patients who are taking antibiotics?
Renal function and diarrhea (looking for C. diff)
What are the age limits on fluroquinolones?
Not for use in people under 18