Musculoskeletal Neoplasms Flashcards

1
Q

Definition of Neoplasm?

A

New Growth

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2
Q

Definition of Tumor?

A

Abnormal mass of tissue

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3
Q

Types of Tumors?

A
  1. Benign

2. Malignant

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4
Q

Definition of Benign?

A

Have no risk of Metastasis (Spreading)

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5
Q

Definition of Malignant?

A

May Metastasize (spread) and are potentially lethal

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6
Q

Definition of Metastatic Cancers?

A

Term reserved for tumors that are form solid tissues and not from blood origin

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7
Q

Types of Metastatic Cancers? (2)

A

Leukemia

Myeloma

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8
Q

Adenocarcinmo:
Sarcoma:
Lymphoma:

A

Adenocarcinoma: Glandular Growth Patterns
Sarcoma: Mesenchymal Elements
Lymphomas: Lymphoid cells

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9
Q

Patients with musculo-skeletal tumors present usually with one or more of the following … (5)

A
  1. Soft Tissue Mass
  2. Bony Mass
  3. Pain
  4. Pathological Fracture
  5. Incidental findings
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10
Q

When analyzing the region of possible cancer growth, what are things you should look for?

A
Swelling
Abnormal Palpations
Abnormal Variance
Distal Neurovascular Function 
Patients Physical Appearance 
Infection
Brusing
Cachexia
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11
Q

If the immune system is impaired, we would expect to find?

A

An Infection

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12
Q

Bruising in cancer patients usually is from …

A

Decreased platelet production

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13
Q

This syndrome is characterized by weight loss, anemia, weakness, and early satiety (feeling of fullness)

A

Cachexia

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14
Q

A System for describing the extent of cancer in the patient’s body.

A

TNM Staging System

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15
Q

What does TNM stand for?

A

T: Describes the size of the TUMOR and whether it has invaded nearby tissues
N: Describes any lymph NODES that are involved
M: Describes METASTASIS (spread of cancer from one body part to another)

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16
Q

This is termed as a Bone Lesion.

A

Osteoid Osteoma

17
Q

Patients who are more prevalent to Osteoid Osteoma range from? (AGE)

18
Q

What type of presentation might one see with Osteoid Osteoma?

A

Constant Dull Pain

Worse At Night

19
Q

For Osteoid Osteoma, what does a Radiological Examination show?

A

Presence of Radiolucent nidus surrounded by well defined oval lesions.

20
Q

For Patients with Osteoid Osteoma, what is a good test for helping making a proper diagnosis?

21
Q

Osteoid Osteoma: best visualization of this type of Lesion ___________
Not as good a tool in defining this type of lesion __________

A

CT Scan (Yes)

MRI (NO)

22
Q

In Osteoid Osteoma, the bone is well __________ and _______ are present

A

Vascularized

Osteoclast Present

23
Q

Treatment for Osteoid Osteoma:
Will resolve without treatment on average of ______
Can use _______ meds until lesion burns out
Surgical excision if patient does not want to endure pain and discomfort
2 Methods _______ & _______

A

33 Months

Anti Inflammatory

Curettage (Cut Out)
Ablation (Destroy Tumor without removing it

24
Q

This is overgrowth of plasma cells int eh bone marrow that can crowd out the normal blood-forming cells.

A

Multiple Myeloma

25
Multiple myeloma can cause ______ -a shortage of red blood cells
Anemia
26
Symptoms of Anemia?
Pale, Weak, and fatigued
27
Multiple Myeloma is a progressive _______ disease
Blood
28
This is the most common primary cancer of bone in adults
Multiple Myeloma
29
Which race is most likely to get Multiple Myeloma?
Afro-American
30
Who is Multiple Myeloma Rare in?
Asians
31
Multiple Myeloma is Unclear, no evidence of hereditary basis, and is only predicted if one is...
Exposed to radiation, petroleum industry, and pesticides
32
Multiple Myeloma clinically presents in a vast majority of patients over ____
40 years
33
Multiple Myeloma clinically presents with what symptoms?
``` Fever Renal Dysfunction Generalized Malaise Nausea Fatigue ```
34
Myeloma can be diagnosed in Blood/urine with high levels of ______
Protein
35
Myeloma can be diagnosed in the blood with high levels of ______ & ______
Calcium and Protein
36
Multiple Myeloma radiological findings show what?
Punched out lesions and bone destruction with little or no reactive bone formation
37
Multiple Myeloma lesions are best seen in the _______ of the body
Skull
38
Is Multiple Myeolma Curable?
No