Musculoskeletal Development (embryo) 11-21-16 Flashcards
Sclerotome forms all the axial skeleton except….
sternum (lateral)
portion of skull(neural crest)
neural crest cells–>mesenchyme–>
viscerocranium and hyoid bone
paraxial mesoderm–> mesenchyme–>
vertebrae, ribs, neurocranium
lateral mesoderm–> mesenchyme–>
pectoral girdle, pelvic girdle, limbs and sternum
each sclerotome segment has a… portion and a… portion
- less dense cranial portion
2. dense caudal portion
Primaxial domain- dorsomedial lip and a few ventrolateral lip cells will form:
muscles of shoulder, back and intercostals
Abaxial domain- most ventrolateral lip myoblasts migrate across the frontier into the lateral plate somatic mesoderm to form:
muscles of infra hyoid, pec major and minor, abs and limbs
Primaxial becomes…
Epaxial (dorsal/posterior)
Abaxial becomes…
Hypaxial (ventral/anterior)
smooth muscle exceptions that are derived from ectoderm
- sphincter and dilator mm. of iris
2. myoepithelial cells of mammary, salivary and sweat glands
Limb bud is a core of…. and is lined by…
- mesenchyme
- surface ectoderm