Blood and hematopoiesis (Histo) 11-14-16 Flashcards
Blood is a … tissue
connective
Blood is composed of… and …
- formed elements
2. plasma
Formed elements of the blood all arise from a … cell
hematopoietic stem
Formed elements of the blood include cells… and… and cell fragments…
- erythrocytes and leukocytes
- thrombocytes (platelets)
Erythrocytes are not…
a true cell (no nucleus)
Plasma is a protein-rich, fluid…
extracellular matrix
Relative volume of RBCs in blood is…. plasma is… and buffy coat is…
RBCs- 45%
plasma- 55%
buffy coat- 1%
The buffy coat is composed of …. and when blood is centrifuged it is… the plasma and RBC layers
- leukocytes and platelets
- between
Place RBCs, buffy coat and plasma in order of decreasing density
- RBCs (most dense)
- buffy coat
- plasma (least dense)
Plasma composition:
90%…
7-8%…
1-2%…
90% water
7-8% plasma proteins
1-2% other solutes
Polymorphonuclear granulocytes have…. and … uncle and also possess…
- specific granules
- multilobed nuclei
- azurophilic granules
3 Polymorphonuclear granulocytes are…
neutrophils
eosinophils
basophils
Mononuclear granulocytes do not have…. have… nuclei and also possess…
- do not have specific granules
- rounded nuclei
- azirophilic granules
4 examples of mononuclear granulocytes are…
- T lymphocytes
- B lymphocytes
- NK cells
- Monocytes
The monophyletic theory is that all
blood cells are derived from a common pluripotential stem cell- hematopoietic stem cell (HSC)
Hematopoietic stem cells are not only capable of differentiating into all blood cell lineages but also capable of…
self renewal because of asymmetric division
HSC can differentiate into these 2 main colonies
- common myeloid progenitor
2. common lymphoid progenitor
What cell in the process of erythropoiesis is no longer capable of cell division?
orthochromatic erythroblast
