Blood and hematopoiesis (Histo) 11-14-16 Flashcards

1
Q

Blood is a … tissue

A

connective

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2
Q

Blood is composed of… and …

A
  1. formed elements

2. plasma

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3
Q

Formed elements of the blood all arise from a … cell

A

hematopoietic stem

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4
Q

Formed elements of the blood include cells… and… and cell fragments…

A
  • erythrocytes and leukocytes

- thrombocytes (platelets)

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5
Q

Erythrocytes are not…

A

a true cell (no nucleus)

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6
Q

Plasma is a protein-rich, fluid…

A

extracellular matrix

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7
Q

Relative volume of RBCs in blood is…. plasma is… and buffy coat is…

A

RBCs- 45%
plasma- 55%
buffy coat- 1%

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8
Q

The buffy coat is composed of …. and when blood is centrifuged it is… the plasma and RBC layers

A
  • leukocytes and platelets

- between

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9
Q

Place RBCs, buffy coat and plasma in order of decreasing density

A
  • RBCs (most dense)
  • buffy coat
  • plasma (least dense)
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10
Q

Plasma composition:
90%…
7-8%…
1-2%…

A

90% water
7-8% plasma proteins
1-2% other solutes

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11
Q

Polymorphonuclear granulocytes have…. and … uncle and also possess…

A
  • specific granules
  • multilobed nuclei
  • azurophilic granules
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12
Q

3 Polymorphonuclear granulocytes are…

A

neutrophils
eosinophils
basophils

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13
Q

Mononuclear granulocytes do not have…. have… nuclei and also possess…

A
  • do not have specific granules
  • rounded nuclei
  • azirophilic granules
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14
Q

4 examples of mononuclear granulocytes are…

A
  • T lymphocytes
  • B lymphocytes
  • NK cells
  • Monocytes
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15
Q

The monophyletic theory is that all

A

blood cells are derived from a common pluripotential stem cell- hematopoietic stem cell (HSC)

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16
Q

Hematopoietic stem cells are not only capable of differentiating into all blood cell lineages but also capable of…

A

self renewal because of asymmetric division

17
Q

HSC can differentiate into these 2 main colonies

A
  1. common myeloid progenitor

2. common lymphoid progenitor

18
Q

What cell in the process of erythropoiesis is no longer capable of cell division?

A

orthochromatic erythroblast