Musculoskeletal Assessment 1 Flashcards
Preop Considerations
Basic patho
Pt’s hx/symptoms/deficits
Current tx/meds to manage disease
What diagnostic tests are indicated/previous results/must be ordered
Anesthetic implications
Rheumatoid arthritis is considered to have ________ manifestations
Systemic
RA Patho
Autoimmune mediated systemic inflammatory disease; characterized by morning stiffness that improves over the course of the day
RA Presentation
pain & disability associated with destruction of synovial joints
RA Presentation
Cellular hyperplasia of the synovium
Painful synovial inflammation with inc synovial fluid
Destruction of cartilage & articular surfaces
Periarticular osteopenia
Ligament damage leading to deformity & instability
In RA, what type of cells causes the activation of endothelial cells that lead to autoantibodies & accelerates inflammatory cascade?
Cytokines
B-lymphocytes
Symptoms of RA
**C-spine mobility (upper cervical spine affected in 85% of patients which can result in atlanto-axial subluxation & spinal cord compression)
Malaise, fatigue, multi-joint inflammation with morning stiffness, hoarseness, HA, accelerated atherosclerosis (increased incidence MI), restrictive lung dz, predisposed to pulmonary infections
RA Hx
onset/course of dz, location/severity of joint dysfunction (C-spine, hoarseness-cricoarytenoid arthritis)
Comorbidities/affected organ systems (hand/wrists involved first, knees most common LE joint)
Management (physical therapy, current meds)
Management of RA
PT, exercise, meds (analgesic, anti-inflammatory, steroids, DMARDS-dz modifying anti-rheumatic drugs)
RA Medications
**Methotrexate (first line drug) → check CBC, LFTs
Corticosteroids → blunt immune response, does not slow progression
DMARDs → slow progression & prevent deformities, target T & B cells
NSAIDs, leflunomide, A TNF agents, IL 1 antagonist
RA Airway exam
Degree of cord compression may not correlate w pt symptoms
-TMJ dz (limits oral opening)
-Arytenoid dz (VC dysfunction) → cricoarytenoid, cricothyroid, TMJ
-Sjogren’s dz (chronic dry mouth leading to poor dentition)
What is a major airway concern for pts with RA?
C-spine instability (50-80% asymptomatic)
Atlanto-axial instability, atlanto-occipital subluxation (pinch SC), cranial settling onto C1 can cause HA & dysphagia, Ankylosis/mobility loss
RA Diagnostic Testing
CBC, metabolic panel, LFT, C-spine flexion/extension
RA Anesthesia Implications
-Airway mgmt (neuro deficit/obstruction risk post op, c-spine eval-want neutral, hoarseness/dysphagia, jaw locking, hx difficult intubation)
-Positioning (maybe pt position self)
-Regional Anesthesia (peripheral nerve block ok, challenging neuraxial block)
What disease process is considered to chronic progressive inflammation of the spine & thorax that causes pain, stiffness, fatigue?
Ankylosing Spondylitis