Musculoskeletal Flashcards

1
Q

TNF-alpha inhibitors

A

Adalimumab and infliximab

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2
Q

Selective COX-2 inhibitors

A
  • Nabumetone
  • Meloxicam
  • Etodolac

More selective :
- Celecoxib : back pain and arthritis

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3
Q

Fenamates and Enolic acids

A
  • Meclofenamate
  • Piroxicam (neutrophil migration inhibition, ^ bleeding)
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4
Q

Acetic acid derivatives

A

Indomethacin, Sulindac (Sulfide), Diclofenac, Tolmetin (RA, OA)

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5
Q

Propionic acid derivatives

A

Ibuprofen, Naproxen, Ketoprofen, Fenoprofen, Flurbiprofen, Oxaprozin

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6
Q

Lipocortin -1

A

Glucosteroids →- lipocostin-1 -→ inhibits AA synthesis by PLAZ

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7
Q

DMARD

A

Hydrochloroquine(Plaquenil), Methotrexate (Rheumatrex),
Leflunomide(Arava)

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