Musculo-Skeletal Flashcards
Name some of the main ECM components
Water, proteins, glycoproteins, proteoglycans.
Name the four types of tissue
Epithelial, nervous, connective, muscular
ECF total water volume?
Two thirds
ICF water content
One third
Give a definition for homeostasis
The maintenance of relatively stable internal conditions in the face of internal or external change.
ECF and ICF values for Na+
135-145 and 10
ECF concentration for Ca2+
2-2.5
Fasting and non fasting blood glucose levels
3.5-6, 3.5-8
Cl- ECF and ICF concentrations
104 and 4
ECF and ICF values for K+
3.5-5 and 150
Four Human tissue act clauses
- Voluntary donation of bodies
- Deceased’s wishes can be overridden
- Indefinite length to hold body
- Avoid unnecessary mutilation of body
Define isoosmotic
Same number of dissolved particles
Define isotonic
No net water movement
What would a lack of potassium give rise to?
Muscle weakness and arrhythmias
What are the four parts of the homeostasis loop.
Controlled variable, sensor, integration centre, effector
What are the five functions of skeletal muscle?
Support, movement, protection, storage, erythropoiesis
Structure of short bone
Cuboidal, lots of cancellous bone.
Function and structure of long bones.
Lever, have epiphyses and diaphysis.
Function of flat bones.
Protection, muscle attachment.
Function of compact bone
Strength (pillar)
Function of cancellous bone?
Shock absorption.
How many of each type of vertebrae are there?
7 cervical, 12 thoracic, 5 lumbar, sacrum, coccyx.
How many of each bone type on the hand?
8 carpal, 5 metacarpal, 3 phalanges except thumb which has 2.
How many of each bone type is there on the foot?
7 tarsal, 5 metatarsal, 3 phalanges except the big toe which has 2
What is the activity of osteoclasts and osteoblasts.
Blasts build class destroy.
What is the ECM proportion of bone, inorganic and organic?
One third organic, two thirds inorganic.
Organic contains a ground substance of what?
Proteoglycans.
The inorganic part of bone is made up of what?
Hydroxyapatite
What do organic and inorganic parts of bone do?
Organic tensile strength and inorganic compression resistance.
Four stages of Haemorrhage
Clot formation
HR increase and vasoconstriction
Blood volume restored
RBC count restored.
What are the components of an osteon?
Made up of lamellae, with osteocytes housed in lacunae, connected to each other via canaliculi. The central canal houses the veins, arteries and nerves.
Contrast cancellous and compact bone
Cancellous has holes and contains trabeculae which are aligned to help distribute force.
Compact is hard and….. Compact.
What is the middle of the bone called?
Medullary cavity
What are the primary and secondary centres of bone growth?
Primary is found in the diaphysis, grow in length, secondary is found in epiphyses, appear postnatal/as an adolescent.