Muscular dystrophy and spinal muscular atrophy

Question 1

most common form of muscular dystrophy

Answer 1

Duchenne

Question 2

Why does Duchenne muscular dystrophy only affect males?

Answer 2

X-Linked

Question 3

the biggest sign of Duchenne muscular dystrophy is…

Answer 3

pseudohypertrophy

Question 4

pseudohypertrophy in duchennes muscular dystrophy means…

Answer 4

myofibrils are destroyed and replaced by fat + connective tissue appearing to be muscular

Question 5

at what age does duchenne muscular dystrophy become apparent

Answer 5

3-5 years

Question 6

A positive (+) of this sign would be putting hands on legs and knees and “walking” them up to get to a standing position

Answer 6

Gower’s sign

Question 7

more severe form of atrophy, results in the destruction of anterior horn cells which destroys LMNs

Answer 7

SMA - Spinal muscular atrophy

Question 8

Matching: DMD or SMA

A) Destruction of LMNs in the anterior horn of the spinal cord
B) Destruction of muscle cells and replacement with fat and connective tissue.

Answer 8

DMD = B
SMA = A