Muscles Flashcards
3 types of muscle
Skeletal - attaches to bones
Cardiac - walls of heart, pumping of heart
Smooth - walls of internal organs (dig. tract)
muscle tissue coverings
Epimysium: surrounds whole muscle
Perimysium: surrounds fascicles within a muscle
Endomysium: surrounds muscle fibers (cells) within a fascicle
Fascia: connective tissue that separates muscles and holds them in position
Deep- surrounds muscle
Subcutaneous- below skin
Subserous- surrounds organs
muscle fatigue
Muscle Fatigue: Inability to contract muscle
Common causes of muscle fatigue: Decreased blood flow Ion imbalances across the sarcolemma Loss of desire to continue exercise Accumulation of lactic acid (controversial)
Cellular Respiration Anaerobic
Anaerobic Phase:
- Glycolysis
- Occurs in cytoplasm
- Produces little ATP
Cellular Respiration Aerobic
Aerobic Phase:
- Citric acid cycle and electron transport system
- Occurs in the mitochondria
- Produces the most ATP
- Myoglobin stores extra oxygen in muscles
Muscle Contraction
- ) Acetylcholine (ACh) is the neurotransmitter
- ) Nerve impulse causes release of ACh from synaptic vesicles
- ) ACh binds to ACh receptors on motor end plate ACh causes changes in membrane permeability to Na+ and K+ ions, which generates a muscle impulse (action potential)
- ) Impulse causes release of Ca+2 from SR, which leads to muscle contraction
Muscle Relaxation
- ) Acetylcholinesterase (enzyme) rapidly decomposes ACh remaining in the synapse
- ) Muscle impulse stops when ACh is decomposed
- ) Stimulus to sarcolemma and muscle fiber membrane ceases
- ) Calcium pump moves Ca+2 back into sarcoplasmic reticulum (SR)
- ) Troponin-tropomyosin complex again covers binding sites on actin
6.)Myosin and actin binding are now prevented
Muscle fiber relaxes
Neuromuscular Junction
Site where an axon of motor neuron and skeletal muscle fiber interact
Parts of a NMJ: Motor neuron Motor end plate Synaptic cleft Synaptic vesicles Neurotransmitters
Myofibrils
Actin - thing filaments
Mysoin - thick filaments
Hypertrophy / Atrophy
Hypertrophy: Enlargement of skeletal muscle that is exercised
Atrophy: Decrease in size and strength of skeletal muscle that is unused
Skeletal Muscle Characteristics
striated
multiple nuclei
voluntary
Smooth Muscle Characteristics
non striated
single nuclei
involuntary
Cardiac Muscle Characteristics
striated
single nuclei
involuntary
2 types of smooth muscle
Multi-unit Smooth Muscle:
Cells are less organized
Iris of eye, walls of blood vessels
Stimulated by neurons, hormones
Visceral Smooth Muscle:
Single-unit smooth muscle; cells respond as a unit
Walls of most hollow organs
More common type of smooth muscle
Muscle Movement:
Agonist
Synergists
Antagonist
Agonist (Prime Mover): muscle that causes an action
Synergists: muscles that assist agonist / prime mover
Antagonist: muscles whose contraction causes movement in the opposite direction of the prime mover