Muscles Flashcards
Muscle
-well developed properties of contraction
-movements of various parts of the body (movement/contractions of organs inside body)
-develops from embryonic mesoderm
3 types: skeletal, cardiac, smooth
Muscle cell Development
- Myoblasts - differentiate from mesoderm
- Myoblasts line up, fuse together, form myotubes
- myotubes are elongated, multinucleate cells
- myotubes create proteins (muscle fibers/cells) to from contractile elements of skeletal muscle
- Satellite cells - mesenchyme-derived myogenic stem cells remain along muscle fibers
- Satellite cells quiescent reserved myoblasts
Muscle Terminology
-Sarcolemma = plasma membrane, extends into interior muscle fiber as tubular invagination (T tubules - transverse)
-Sarcoplasm = cytoplasm
-sacroplasmic reticulum = smooth endoplasmic reticulum sores intercellular calcium
-muscle fiber = muscle cell
-myofibrils = long contractile elements
sarcomere = individual contractile unit found each myofibril
skeletal muscle
-pink/red due to blood supply and presence of myoglobin (transport oxygen)
-Three types:
1. Red (slow, type 1)
2. intermediate (type 2a)
3. white (fast, type 2b)
-innervation of muscle fibers appears to influence fiber type
Skeletal muscle
-collagenous connective tissue
1. epimysium - surrounds entire muscle
2. perimysium - surrounds bundles of muscle fibers (fascicles)
-reticular connective tissue
1. endomysium - surrounds each muscle cell and includes basal lamina
Skeletal muscle morphology
-fibers are long cylinders
-multinucleated
-nuclei located peripherally
-muscle fibers appear striated (striped) when seen longitudinally due to light and dark bands result from specific orientation of contractile proteins