muscle structure and function Flashcards
sarcolemma
muscle cell membrane
sarcoplasm
contains nuclei that contains the genes, mitochondria, and other specialized organelles
myofibrils
threadlike strands within muscle fibers
actin
thin filament
myosin
thick filament
sarcomere
z line, m line, h zone, a band, and I band
I band
lighter area in myofibril
a band
darker area in myofibril
h zone
center of a band
m band
bisects the H zone and consists of protein structures that support the arrangement of myosin filaments
z line
bisects I band and adheres to sarcolemma to provide stability
concentric
reduction in the distance between z lines of the sarcomere
isometric muscle
the fibers length remains unchanged, same spacing of I band and a band
eccentric action
a band widens as the fiber lengthens during force generation
motor end plate
pocket formed around motor neuron by sarcolemma
neuromuscular cleft
short gap where Ach is released by motor neuron
step 1
action potential in motor neuron has axon terminal release Ach to diffuse across the synaptic cleft and attach to specific receptor on sarcolemma
step 2
action potential depolarizes the transverse tubules at sarcomeres A-I junction
step 3
depolarization of t tubule releases Calcium from the sarcoplasmic reticulum
step 4
calcium binds to troponin and tropomyosin in the actin filaments, releases inhibition that had previously prevented actin from attaching to myosin
step 5
actin combines with myosin- myosin activates ATPase which splits ATP, this makes the crossbridge and tension
step 6
ATP binds to myosin crossbridge breaking the actin and myosin bond (actin dissociates from actin) the thick and thin filaments slide past each other and the muscle shortens
step 7
crossbridge continues when calcium remains high enough to inhibit troponin and tropomyosin
step 8
muscle stimulation stops, calcium rapidly decreases and calcium moves back to sarcoplasmic reticulum through active transport