Muscle physiology Flashcards
3 types of muscle:
- smooth
- skeletal
- cardiac
What is skeletal muscle?
voluntary, striated muscle making up 40% of body mass
sarcomere
- smallest functional unit of skeletal and cardiac muscle
- shorten and expand with contractions
thick filament
has globulin head allowing it to interact with thin filament for muscle contraction
thin filaments function
slide over thick filaments toward centre of sarcomere to produce contraction
What are the 4 proteins of thin filaments?
- f actin
- tropomyosin
- troponin
- nebulin
what is involved in the planning of movement?
prefrontal cortex and premotor area of brain
What is a neuromuscular junction?
synapse between motor neurone and skeletal muscle fibre
Excitation contraction coupling:
contraction by causing calcium release by AP
Relaxation phase:
calcium pumps back into sarcoplasmic reticulum via active transport allowing myosin heads to disengage from actin
Contration:
Ca+ is released from SR, binds to troponin, and moves tropomyosin allowing access to myosin binding sites
What are the 3 phases of muscle twitch?
- Latent- delay after action potential
- Contraction- Calcium release allows cross bridge
- Relaxation- tension is reduced
cause of muscle fatigue
loss of ATP
what is a motor unit
a motorneuron and all the muscle fibres it innervates
define isometric strength test
tension without contraction