Muscle Contraction Flashcards
What is involuntary muscle?
Smooth muscle found in the wall of tubular structures like blood vessels which is controlled unconsciously by the autonomic nervous system.
What is cardiac muscle?
This from the muscular part of the heart which is myogenic meaning it contracts on its own
What is skeletal muscle?
occurs at the joints in the skeleton and is composes of muscle fibres
What do muscle fibres consist of?
they are fibres containing many nuclei and enclosed by a membrane called the sarcolemma. contain a cytoplasm called the sarcoplasm which is specialised with many mitochondria and a specialised endoplasmic reticulum.
What are myofibrils?
Contained in muscle fibres and is divided into sarcomeres containing protein filaments , actin and myosin.
What are light bands?
No overlap between actin and myosin
What are dark bands?
An overlap between actin and myosin
What is the Z line?
Line at the centre of s light band
what is a sarcomere?
The distance between 2 Z lines
What is the H zone?
The light section of the dark band
What is the process at a neuromuscular junction?
- Action potential arrives at the end of the axon and open the calcium channel which causes calcium to flood the axon
- Vesicles of acetylcholine move towards and fuse with the end membrane
- Molecules diffuse across gap and fuse with receptors on the sarcolemma
- causes sodium ion channel to open and sodium enters the muscle fibre causing depolarisation of sarcolemma
- wave of depolarisation spread along sarcolemma and down traverse tube in muscle fibre.
What is the sliding filament hypothesis?
During contraction the light band and the H zone get shorter and the Z lines move closer together and the sarcomere shortens so the thick and thin slide over each other
What is the process of muscle contraction?
- the muscle is stimulated
- action potential causes a release of calcium
- calcium binds to troponin which alters its shape and pulls the tropomyosin to the side exposing the actin binding sites
- myosin heads bind to the actin which forms cross bridges between the filaments
- myosin head moves pulling actin past myosin
- myosin then detaches and can bind again further up the actin filament.
What is the role of ATP?
Supplies the energy for muscle contraction
How is the supply of ATP maintained (3 ways)?
- Aerobic respiration in mitochondria
- anaerobic respiration in sarcoplasm
- Creatine Phosphate in sarcoplasm