Muscarinic Antagonists (anti-ACh)

Question 1

ATROPINE
(HOMATROPINE)
(TROPICAMIDE)

Answer 1

Muscarinic Antagonist (blocks ACh, PNS)

Eye: mydriasis (dilated)

Question 2

BENZTROPINE

Answer 2

Muscarinic Antagonist (blocks ACh, PNS)

“park my BENZ”

for Parkinson disease/acute dystonia

Question 3

GLYCOPYRROLATE

Answer 3

Muscarinic Antagonist (blocks ACh, PNS)

GI: drooling, peptic ulcer
Resp: pre-op to reduce airway secretions

Question 4

HYOSCYAMINE

(DICYCLOMINE)

Answer 4

Muscarinic Antagonist (blocks ACh, PNS)

GI: anti-spasmadic for IBS

“HI, OSKI, don’t spaz out ON ME”

Question 5

IPRATROPIUM

(TIOTROPIUM)

Answer 5

Muscarinic Antagonist (blocks ACh, PNS)

Resp: COPD, asthma

“I PRAy I can breathe soon!”

Question 6

OXYBUTYNIN
(SOLIFENACIN)
(TOLTERODINE)

Answer 6

Muscarinic Antagonist (blocks ACh, PNS)

GU: anti-spasms of bladder + reduces urge incontinence (overactive bladder)

Question 7

SCOPOLAMINE

Answer 7

Muscarinic Antagonist (blocks ACh, PNS)

CNS: for motion sickness

“marCO POLo, SCOPOLo, gets motion sickness from all his travels at sea”

Question 8

ATROPINE

what’re its actions…

Answer 8

AnTi-PNs (ATroPiNe)

action: ^pupil dilation; lowers all WET (M3)

Question 9

ATROPINE

what’re its side-effects…

Answer 9

opposite of WET (M3) b/c AnTi-PNs

HOT as a hare (no sweating)
DRY as a bone (no saliva, urinating)
RED as a beet (rapid pulse)
BLIND as a bat (acute angle-closure glaucoma)
MAD as a hatter (disorientation)