Murphy

Question 0

How to address first dose syncope adverse effect of Alpha 1 blocker

Answer 0

First dose should be given at bedtime, patient should be instructed to rise slowly to decrease risk if orthostatic hypotension and syncope

Question 1

CCBs contraindications

Answer 1

2/3 degree heart block
Cardiogenic shock
Acute MI
Systolic heart failure

Question 2

Beta blocker contraindications

Answer 2

HR < 60 
SBP < 90 mm hg 
Severe asthma or COPD
Heart block
Decompensated HF

Question 3

Example of alpha-2 agonists

Answer 3

Clonidine

Methyldopa

Question 4

Aldosterone antagonist has minimal _____ effect, but beneficial when used as add-on therapy

Answer 4

Antihypersensitve

Question 5

If you prescribed these classes of drug with diuretics, cut starting dose in half

Answer 5

ACEI

ARBs

Question 6

Antihypersensitive Drug that can be initiated in pregnancy

Answer 6

Methyldopa
Labetalol
Long-acting nifedipine
Hydralazine

Question 7

Standard combination therapy in HF

Answer 7

ACEI + B-blocker + Diuretic

Question 8

Spironolactone is indicated as add on therapy for HF when

Answer 8

CrCl>30ml/min

k < 5 meq/dl

Question 9

3 ARBs that have best evidence for reducing preload and afterload

Answer 9

Candesartan (most helpful)
Losartan
Valsartan

Question 10

Which drugs used in HF reduce mortality and morbidity?

Answer 10

ACEI
Arbs
B-blocker
Spirinolactone

Question 11

In heart failure, initiate spironolactone when _____ in men, ____ in women and potassium ______

Answer 11

Scr < 2.5
Scr < 2
< 5

Question 12

Chlorthalidone daily dosage range

Answer 12

12.5 - 50 range

Question 13

ACEI is ______ in diabetic patient

Answer 13

Renoprotective

Question 14

ACEI & ARBs absolute contraindications

Answer 14

Pregnancy(2nd & 3rd trimester)
Angiodema
Bilateral renal artery stenosis

Question 15

You can substitute ________ for b-blocker in patient with CAD

Answer 15

Long acting CCB ( verapamil or diltiazem)

Question 16

List drugs that treat diabetic hypertensive patient in order of importance

Answer 16

ACEI or arbs
Dhp-CCB
Thiazides
B-blocker

Question 17

Post-MI patient should be on ___ and ____ unless absolutely contraindicated

Answer 17

ACEI

B-blocker

Question 18

JNC-8 recommends if goal blood pressure not reached within ___ month of treatment, increasing dose or start a second drug

Answer 18

1

Question 19

CCBs may reduce proteinuria in patient with _____

Answer 19

CKD

Question 20

____ release CCBs are preferred in HTN patient

Answer 20

Extended

Question 21

Which CCB should be avoided in patient with acute MI

Answer 21

Diltiazem

Question 22

Beta blocker may mask signs of _______

Answer 22

Hypoglycemia